Bases Moleculares de los Sistemas Biológicos (SIBIUMA)
Lineas de Investigación
01. Angiogénesis y microentorno tumoral: Identificación y caracterización de moduladores de angiogénesis. Metabolismo en el microentorno tumoral.
02. Metabolismo de aminas biógenas y poliaminas en la salud y la enfermedad.
03. Bioinformática y redes: Modelos de interactomas, redes de enfermedad y de fármacos con métodos predictivos.
04. Flujos de trabajo bioinformáticos para la automatizacion de análisis genómicos. Análisis de expresión de transposones en cáncer.
05. Aplicaciones de las líneas 1-4 a las enfermedades raras.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
PLAN PROPIO_AREA 5_2020 Área 5. IBIMA Rare: Enfermedades raras
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
PID2019-108096RB-C21 Aproximaciones sistémicas basadas en asociaciones fenotipo-genotipo para mejorar el diagnóstico de pacientes con enfermedades raras
Ministerio de Asuntos Económicos y Transformación Digital
.
2020
PID2019-105010RB-I00. ANGIOGENESIS, INFLAMACION Y METABOLISMO COMO DIANAS TERAPEUTICAS DE LA ANGIOGENESIS PATOLOGICA EMPLEANDO ENFOQUES BIOTECNOLOGICOS
Ministerio de Asuntos Económicos y Transformación Digital
.
2020
PI-0075-2017 Utilización de Datos Clínicos E In Vitro para Desarrollar Un Modelo Predictivo de la Alergenicidad de Proteínas Vegetales de la Familia Ltp Mediante Métodos Bioinformáticos de Aprendizaje Autómatico.
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2017
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Antiangiogenic Phytochemicals Constituent of Diet as Promising Candidates for Chemoprevention of Cancer
Marrero AD, Quesada AR, Martínez-Poveda B, Medina MÁ Antioxidants (Basel, Switzerland) 2022 Jan 31;11(2):
A problem-/case-based learning approach as an useful tool for studying glycogen metabolism and its regulation
García-Ponce ÁL, Martínez-Poveda B, Blanco-López Á, Quesada AR, Suárez F, et al. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2021 Mar;49(2):236-241
Bringing Light to Science Undergraduate Students: A Successful Laboratory Experiment Illustrating the Principles and Applications of Bioluminescence
Garcia-Ponce, AL; Torres-Vargas, JA; Garcia-Caballero, M; Medina, MA; Blanco-Lopez, A; Quesada, AR JOURNAL OF CHEMICAL EDUCATION 2021
Chromosome anchoring in Senegalese sole (Solea senegalensis) reveals sex-associated markers and genome rearrangements in flatfish
Guerrero-Cózar I, Gomez-Garrido J, Berbel C, Martinez-Blanch JF, Alioto T, et al. Scientific reports 2021 Jun 29;11(1):13460
Decoding Neuromuscular Disorders Using Phenotypic Clusters Obtained From Co-Occurrence Networks
Díaz-Santiago E, Claros MG, Yahyaoui R, de Diego-Otero Y, Calvo R, et al. Frontiers in molecular biosciences 2021;8():635074
Demography, genetic diversity and expansion load in the colonizing species Leontodon longirostris (Asteraceae) throughout its native range
de Pedro M, Riba M, González-Martínez SC, Seoane P, Bautista R, et al. Molecular ecology 2021 Mar;30(5):1190-1205
Evaluating, Filtering and Clustering Genetic Disease Cohorts Based on Human Phenotype Ontology Data with Cohort Analyzer
Rojano E, Córdoba-Caballero J, Jabato FM, Gallego D, Serrano M, et al. Journal of personalized medicine 2021 Jul 27;11(8):
From Food to Genes: Transcriptional Regulation of Metabolism by Lipids and Carbohydrates
Bravo-Ruiz I, Medina MÁ, Martínez-Poveda B Nutrients 2021 Apr 30;13(5):
Sustainability in the management of scientific information
Medina, MA SUSTAINABILITY SCIENCE 2021
Gene expression analysis method integration and co-expression module detection applied to rare glucide metabolism disorders using ExpHunterSuite
Jabato FM, Córdoba-Caballero J, Rojano E, Romá-Mateo C, Sanz P, et al. Scientific reports 2021 Jul 23;11(1):15062
Genetic Estimates for Growth and Shape-Related Traits in the Flatfish Senegalese Sole
Guerrero-Cozar I, Jimenez-Fernandez E, Berbel C, Espinosa E, Claros MG, et al. Animals : an open access journal from MDPI 2021 Apr 22;11(5):
Genetic parameter estimates and identification of SNPs associated with growth traits in Senegalese sole
Guerrero-Cozar, I; Jimenez-Fernandez, E; Berbel, C; Cordoba-Caballero, J; Claros, MG; Zerolo, R; Manchado, M AQUACULTURE 2021
Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug-Induced Acute Urticaria/Angioedema
Jurado-Escobar R, Doña I, Triano-Cornejo J, Perkins JR, Pérez-Sánchez N, et al. Frontiers in pharmacology 2021;12():667824
Histamine, Metabolic Remodelling and Angiogenesis: A Systems Level Approach
Moya-García AA, Pino-Ángeles A, Sánchez-Jiménez F, Urdiales JL, Medina MÁ Biomolecules 2021 Mar 11;11(3):
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus
Ojeda-Pérez B, Campos-Sandoval JA, García-Bonilla M, Cárdenas-García C, Páez-González P, et al. Fluids and barriers of the CNS 2021 Jul 2;18(1):30
NGS of microRNAs Involved in Cardioprotection Induced by Sevoflurane Compared to Propofol in Myocardial Revascularization Surgery: The ACDHUVV-16 Clinical Trial
Orriach JLG, Belmonte JJE, Aliaga MR, Fernandez AR, Capitan MJR, et al. Current medicinal chemistry 2021;28(20):4074-4086
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Cárdenas C, Torres-Vargas JA, Cárdenas-Valdivia A, Jurado N, Quesada AR, et al. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144():112263
Polymorphisms in eicosanoid-related biosynthesis enzymes associated with acute urticaria/angioedema induced by nonsteroidal anti-inflammatory drug hypersensitivity
Jurado-Escobar R, Doña I, Perkins JR, Laguna JJ, Muñoz-Cano R, et al. The British journal of dermatology 2021 Oct;185(4):815-824
Protein residues determining interaction specificity in paralogous families
Pitarch B, Ranea JAG, Pazos F Bioinformatics (Oxford, England) 2021 May 23;37(8):1076-1082
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate
Vega-Granados K, Cruz-Reyes J, Horta-Marrón JF, Marí-Beffa M, Díaz-Rubio L, et al. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2021 Feb;34(1):107-117
Systematic identification of genetic systems associated with phenotypes in patients with rare genomic copy number variations
Jabato FM, Seoane P, Perkins JR, Rojano E, García Moreno A, et al. Human genetics 2021 Mar;140(3):457-475
Tumor vessel co-option probed by single-cell analysis
Teuwen LA, De Rooij LPMH, Cuypers A, Rohlenova K, Dumas SJ, et al. Cell reports 2021 Jun 15;35(11):109253
A comparative study of the antiangiogenic activity of hydroxytyrosyl alkyl ethers
Marrero AD, Castilla L, Espartero JL, Madrona A, R Quesada A, et al. Food chemistry 2020 Dec 15;333():127476
Advances in the Knowledge of the Molecular Biology of Glioblastoma and Its Impact in Patient Diagnosis, Stratification, and Treatment
Delgado-Martín B, Medina MÁ Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 May;7(9):1902971
An improved de novo assembling and polishing of Solea senegalensis transcriptome shed light on retinoic acid signalling in larvae
Córdoba-Caballero J, Seoane P, Jabato FM, Perkins JR, Manchado M, et al. Scientific reports 2020 Nov 26;10(1):20654
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus
Caro-Astorga J, Frenzel E, Perkins JR, Álvarez-Mena A, de Vicente A, et al. NPJ biofilms and microbiomes 2020;6():3
Control of tumor angiogenesis and metastasis through modulation of cell redox state
Serrano JJ, Delgado B, Medina MÁ Biochimica et biophysica acta. Reviews on cancer 2020 Apr;1873(2):188352
Development of whole-genome multiplex assays and construction of an integrated genetic map using SSR markers in Senegalese sole
Guerrero-Cózar I, Perez-Garcia C, Benzekri H, Sánchez JJ, Seoane P, et al. Scientific reports 2020 Dec 14;10(1):21905
Expression-based, consistent biomarkers for prognosis and diagnosis in lung cancer
Arroyo M, Larrosa R, Gómez-Maldonado J, Cobo MÁ, Claros MG, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Oct;22(10):1867-1874
Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner
Ocaña MC, Martínez-Poveda B, Marí-Beffa M, Quesada AR, Medina MÁ Scientific reports 2020 Apr 9;10(1):6132
Gene Expression Profile of Mexican Lime ( Citrus aurantifolia) Trees in Response to Huanglongbing Disease caused by Candidatus Liberibacter asiaticus
Arce-Leal ÁP, Bautista R, Rodríguez-Negrete EA, Manzanilla-Ramírez MÁ, Velázquez-Monreal JJ, et al. Microorganisms 2020 Apr 7;8(4):
Glucose Favors Lipid Anabolic Metabolism in the Invasive Breast Cancer Cell Line MDA-MB-231
Ocaña MC, Martínez-Poveda B, Quesada AR, Medina MÁ Biology 2020 Jan 10;9(1):
Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival
Rodriguez-Losada N, Wendelbob R, Ocaña MC, Casares AD, Guzman de Villoría R, et al. Frontiers in neuroscience 2020;14():570409
High-strength low-modulus biocompatible Nb-1Zr alloy processed by accumulative roll bonding
Rodriguez-Espinoza, BL; Garcia-Pastor, FA; Martinez-Poveda, B; Quesada, AR; Lopez-Crespo, P MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING 2020
In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves
Rey-Blanes C, Pérez-Portero Y, Morris-Quevedo HJ, Casas V, Abdala R, et al. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131():110716
Metabolic Reprogramming is a Hallmark of Metabolism Itself
Medina MÁ, Medina MÁ BioEssays : news and reviews in molecular, cellular and developmental biology 2020 Oct;42(10):e2000058
Phenotype-genotype comorbidity analysis of patients with rare disorders provides insight into their pathological and molecular bases
Díaz-Santiago E, Jabato FM, Rojano E, Seoane P, Pazos F, et al. PLoS genetics 2020 Oct;16(10):e1009054
A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations
Ashford P, Pang CSM, Moya-García AA, Adeyelu T, Orengo CA Scientific reports 2019 Jan 22;9(1):263
Biomarker potential of repetitive-element transcriptome in lung cancer
Arroyo M, Bautista R, Larrosa R, Cobo MÁ, Claros MG PeerJ 2019;7():e8277
Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria
Doña I, Jurado-Escobar R, Perkins JR, Ayuso P, Plaza-Serón MC, et al. Allergy 2019 Jun;74(6):1135-1144
Exploring the Antiangiogenic Potential of Solomonamide A Bioactive Precursors: In Vitro and In Vivo Evidences of the Inhibitory Activity of Solo F-OH During Angiogenesis
Carrillo P, Martínez-Poveda B, Cheng-Sánchez I, Guerra J, Tobia C, et al. Marine drugs 2019 Apr 15;17(4):
Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model
Rodriguez MJ, Ramos-Soriano J, Perkins JR, Mascaraque A, Torres MJ, et al. Scientific reports 2019 Mar 11;9(1):4043
Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions
Ocaña MC, Martínez-Poveda B, Quesada AR, Medina MÁ Biomolecules 2019 Aug 1;9(8):
Immunomodulatory and Antioxidant Activities of Sulfated Polysaccharides from Laminaria ochroleuca, Porphyra umbilicalis, and Gelidium corneum
Abdala Díaz RT, Casas Arrojo V, Arrojo Agudo MA, Cárdenas C, Dobretsov S, et al. Marine biotechnology (New York, N.Y.) 2019 Aug;21(4):577-587
Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic target
Ocaña MC, Martínez-Poveda B, Quesada AR, Medina MÁ Medicinal research reviews 2019 Jan;39(1):70-113
Nitric oxide-dependent regulation of sweet pepper fruit ripening
González-Gordo S, Bautista R, Claros MG, Cañas A, Palma JM, et al. Journal of experimental botany 2019 Aug 29;70(17):4557-4570
Not all has been said about glucose oxidase/peroxidase: New pedagogical uses for a classical and robust undergraduate laboratory experiment
García-Ponce ÁL, Martínez-Poveda B, Blanco-López Á, Medina MÁ, Quesada AR Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2019 May;47(3):341-347
Polyamines in mammalian pathophysiology
Sánchez-Jiménez F, Medina MÁ, Villalobos-Rueda L, Urdiales JL Cellular and molecular life sciences : CMLS 2019 Oct;76(20):3987-4008
Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs
Perkins JR, Acosta-Herrera M, Plaza-Serón MC, Jurado-Escobar R, Doña I, et al. The pharmacogenomics journal 2019 Apr;19(2):191-199
Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients
Palomares F, Ramos-Soriano J, Gomez F, Mascaraque A, Bogas G, et al. Molecular nutrition & food research 2019 Oct;63(20):e1900553
RNA-seq analysis and fluorescence imaging of melon powdery mildew disease reveal an orchestrated reprogramming of host physiology
Polonio Á, Pineda M, Bautista R, Martínez-Cruz J, Pérez-Bueno ML, et al. Scientific reports 2019 May 28;9(1):7978
Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol
Cheng-Sánchez I, Torres-Vargas JA, Martínez-Poveda B, Guerrero-Vásquez GA, Medina MÁ, et al. Marine drugs 2019 Aug 23;17(9):
TarSynFlow, a workflow for bacterial genome comparisons that revealed genes putatively involved in the probiotic character of Shewanella putrefaciens strain Pdp11
Seoane P, Tapia-Paniagua ST, Bautista R, Alcaide E, Esteve C, et al. PeerJ 2019;7():e6526
The haustorial transcriptome of the cucurbit pathogen Podosphaera xanthii reveals new insights into the biotrophy and pathogenesis of powdery mildew fungi
Polonio Á, Seoane P, Claros MG, Pérez-García A BMC genomics 2019 Jul 4;20(1):543
The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer
Martínez-Poveda B, Torres-Vargas JA, Ocaña MDC, García-Caballero M, Medina MÁ, et al. Nutrients 2019 Aug 31;11(9):
The strigolactone analog GR-24 inhibits angiogenesis in vivo and in vitro by a mechanism involving cytoskeletal reorganization and VEGFR2 signalling.
Carrillo P, Martínez-Poveda B, Medina MÁ, Quesada AR Biochemical pharmacology 2019 Oct;168():366-383
Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food-Antigen-Induced Anaphylaxis Reveals the Upregulation of Multiple Immune-Related Pathways
Rodriguez MJ, Palomares F, Bogas G, Torres MJ, Diaz-Perales A, et al. Molecular nutrition & food research 2019 Feb;63(3):e1800759
(+)-Aeroplysinin-1 Modulates the Redox Balance of Endothelial Cells
García-Vilas JA, Martínez-Poveda B, Quesada AR, Medina MÁ Marine drugs 2018 Sep 6;16(9):
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
López-Jiménez A, Gallardo E, Espartero JL, Madrona A, Quesada AR, et al. Food & function 2018 Aug 15;9(8):4310-4316
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sánchez LB, Marí-Beffa M, Carrillo P, Medina MÁ, Díaz-Cuenca A Acta biomaterialia 2018 Mar 1;68():272-285
Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors
Cheng-Sánchez I, Carrillo P, Sánchez-Ruiz A, Martínez-Poveda B, Quesada AR, et al. The Journal of organic chemistry 2018 May 18;83(10):5365-5383
Fishing anti(lymph)angiogenic drugs with zebrafish
García-Caballero M, Quesada AR, Medina MA, Marí-Beffa M Drug discovery today 2018 Feb;23(2):366-374
Mathematical modeling of cancer metabolism
Medina MÁ, Medina MÁ Critical reviews in oncology/hematology 2018 Apr;124():37-40
Phenotype-loci associations in networks of patients with rare disorders: application to assist in the diagnosis of novel clinical cases
Bueno A, Rodríguez-López R, Reyes-Palomares A, Rojano E, Corpas M, et al. European journal of human genetics : EJHG 2018 Oct;26(10):1451-1461
Regulatory role of microRNA in mesenteric lymph nodes after &ITSalmonella&IT Typhimurium infection
Herrera-Uribe J, Zaldívar-López S, Aguilar C, Luque C, Bautista R, et al. Veterinary research 2018 Feb 1;49(1):9
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Seoane P, Espigares M, Carmona R, Polonio Á, Quintana J, et al. BMC bioinformatics 2018 Nov 20;19(Suppl 14):416
Updates on the hepatocyte growth factor/c-Met axis in hepatocellular carcinoma and its therapeutic implications
García-Vilas JA, Medina MÁ World journal of gastroenterology 2018 Sep 7;24(33):3695-3708
What We Know and What We Need to Know about Aromatic and Cationic Biogenic Amines in the Gastrointestinal Tract
Fernández-Reina A, Urdiales JL, Sánchez-Jiménez F Foods (Basel, Switzerland) 2018 Sep 4;7(9):
Automated identification of reference genes based on RNA-seq data
Carmona R, Arroyo M, Jiménez-Quesada MJ, Seoane P, Zafra A, et al. Biomedical engineering online 2017 Aug 18;16(Suppl 1):65
Development of genomic tools in a widespread tropical tree, Symphonia globulifera L.f.: a new low-coverage draft genome, SNP and SSR markers
Olsson S, Seoane-Zonjic P, Bautista R, Claros MG, González-Martínez SC, et al. Molecular ecology resources 2017 Jul;17(4):614-630
Generation of nitric oxide by olive (Olea europaea L.) pollen during in vitro germination and assessment of the S-nitroso- and nitro-proteomes by computational predictive methods
Jimenez-Quesada MJ, Carmona R, Lima-Cabello E, Traverso JÁ, Castro AJ, et al. Nitric oxide : biology and chemistry 2017 Aug 1;68():23-37
Genomic analysis of the marine fish pathogen Photobacterium damselae subsp piscicida: Insertion sequences proliferation is associated with chromosomal reorganisations and rampant gene decay
Balado M, Benzekri H, Labella AM, Claros MG, Manchado M, et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017 Oct;54():221-229
Homocysteine pre-treatment increases redox capacity in both endothelial and tumor cells
Díaz-Santiago E, Rodríguez-Caso L, Cárdenas C, Serrano JJ, Quesada AR, et al. Redox report : communications in free radical research 2017 Jul;22(4):183-189
Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis
García-Vilas JA, Quesada AR, Medina MÁ Food chemistry 2017 Apr 15;221():1741-1746
Identification and Functional Annotation of Genes Differentially Expressed in the Reproductive Tissues of the Olive Tree (Olea europaea L.) through the Generation of Subtractive Libraries
Zafra A, Carmona R, Traverso JA, Hancock JT, Goldman MHS, et al. Frontiers in plant science 2017;8():1576
Pleiotropic Role of Puupehenones in Biomedical Research
Martínez-Poveda B, Quesada AR, Medina MÁ Marine drugs 2017 Oct 21;15(10):
Polyamine-RNA-membrane interactions: From the past to the future in biology
Acosta-Andrade C, Artetxe I, Lete MG, Monasterio BG, Ruiz-Mirazo K, et al. Colloids and surfaces. B, Biointerfaces 2017 Jul 1;155():173-181
Structural and Functional View of Polypharmacology
Moya-García A, Adeyelu T, Kruger FA, Dawson NL, Lees JG, et al. Scientific reports 2017 Aug 31;7(1):10102
Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases
García-Caballero M, Paupert J, Blacher S, Van de Velde M, Quesada AR, et al. Journal of hematology & oncology 2017 Jun 19;10(1):122
The Natural Antiangiogenic Compound AD0157 Induces Caspase-Dependent Apoptosis in Human Myeloid Leukemia Cells
García-Caballero M, Martínez-Poveda B, Medina MA, Quesada AR Frontiers in pharmacology 2017;8():802
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
García-Vilas JA, Pino-Ángeles A, Martínez-Poveda B, Quesada AR, Medina MÁ Cancer letters 2017 Jan 28;385():1-11
A novel role for antizyme inhibitor 2 as a regulator of serotonin and histamine biosynthesis and content in mouse mast cells
Acosta-Andrade C, Lambertos A, Urdiales JL, Sánchez-Jiménez F, Peñafiel R, et al. Amino acids 2016 Oct;48(10):2411-21
Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug
García-Vilas JA, Martínez-Poveda B, Quesada AR, Medina MÁ Marine drugs 2015 Dec 22;14(1):1
Characterisation of non-coding genetic variation in histamine receptors using AnNCR-SNP
Rojano E, Ranea JA, Perkins JR Amino acids 2016 Oct;48(10):2433-42
Conventional Matrices Loaded Onto a Graphene Layer Enhances MALDI-TOF/TOF Signal: Its Application to Improve Detection of Phosphorylated Peptides
Rodríguez CE, Palacios J, Fajardo I, Urdiales JL, Le Guével X, et al. Journal of the American Society for Mass Spectrometry 2016 Feb;27(2):366-9
Establishing gene models from the Pinus pinaster genome using gene capture and BAC sequencing
Seoane-Zonjic P, Cañas RA, Bautista R, Gómez-Maldonado J, Arrillaga I, et al. BMC genomics 2016 Feb 27;17():148
Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies
Bueno A, Morilla I, Diez D, Moya-Garcia AA, Lozano J, et al. Oncotarget 2016 Nov 15;7(46):75810-75826
Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway
García-Caballero M, Blacher S, Paupert J, Quesada AR, Medina MA, et al. British journal of pharmacology 2016 Jun;173(12):1966-87
Systematic identification of phenotypically enriched loci using a patient network of genomic disorders
Reyes-Palomares A, Bueno A, Rodríguez-López R, Medina MÁ, Sánchez-Jiménez F, et al. BMC genomics 2016 Mar 15;17():232
Transcriptional analysis of porcine intestinal mucosa infected with Salmonella Typhimurium revealed a massive inflammatory response and disruption of bile acid absorption in ileum
Uribe JH, Collado-Romero M, Zaldívar-López S, Arce C, Bautista R, et al. Veterinary research 2016 Jan 7;47():11
Whole-exome sequencing analysis in twin sibling males with an anterior cruciate ligament rupture
Caso E, Maestro A, Sabiers CC, Godino M, Caracuel Z, et al. Injury 2016 Sep;47 Suppl 3():S41-S50
Damnacanthal inhibits IgE receptor-mediated activation of mast cells
Garcia-Vilas JA, Medina MA, Melo FR, Pejler G, Garcia-Faroldi G Molecular immunology 2015 May;65(1):86-93
Damnacanthal, a noni anthraquinone, inhibits c-Met and is a potent antitumor compound against Hep G2 human hepatocellular carcinoma cells
García-Vilas JA, Quesada AR, Medina MA Scientific reports 2015 Jan 26;5():8021
FUN-L: gene prioritization for RNAi screens
Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, et al. Bioinformatics (Oxford, England) 2015 Jun 15;31(12):2052-3
Identifying and characterising key alternative splicing events in Drosophila development
Lees JG, Ranea JA, Orengo CA BMC genomics 2015 Aug 16;16():608
kpath: integration of metabolic pathway linked data
Navas-Delgado I, García-Godoy MJ, López-Camacho E, Rybinski M, Reyes-Palomares A, et al. Database : the journal of biological databases and curation 2015;2015():bav053
Large-Scale Transcriptome Analysis in Faba Bean (Vicia faba L.) under Ascochyta fabae Infection
Ocaña S, Seoane P, Bautista R, Palomino C, Claros GM, et al. PloS one 2015;10(8):e0135143
Metabolic restructuring and cell fate conversion
Prigione A, Ruiz-Pérez MV, Bukowiecki R, Adjaye J Cellular and molecular life sciences : CMLS 2015 May;72(9):1759-77
Polyamine Metabolism Is Sensitive to Glycolysis Inhibition in Human Neuroblastoma Cells
Ruiz-Pérez MV, Medina MÁ, Urdiales JL, Keinänen TA, Sánchez-Jiménez F The Journal of biological chemistry 2015 Mar 6;290(10):6106-19
ReprOlive: a database with linked data for the olive tree (Olea europaea L.) reproductive transcriptome
Carmona R, Zafra A, Seoane P, Castro AJ, Guerrero-Fernández D, et al. Frontiers in plant science 2015;6():625
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