Obesidad, diabetes y sus comorbilidades: prevención y tratamiento
Lineas de Investigación
01. Microflora intestinal, resistencia a la insulina y obesidad.
02. Papel de la adipobiología en las enfermedades metabólicas.
03. Efecto metabólico de la cirugía bariátrica.
04. Factores ambientales en la génesis de obesidad y diabetes.
05. Nuevos mecanismos celulares y moleculares de la inflamación en las enfermedades metabólicas: obesidad, diabetes y cáncer.
06. Factores genéticos y epigenéticos en la prevención, evolución y tratamiento de la diabetes.
07. Estudio PREDIMED PLUS.
08. Abordaje dietoterápico de la obesidad: papel de la cetosis, ayuno intermitente, ejercicio físico y cronobiología.
09. Fitness mitocondrial en enfermedades metabólicas.
10. Complicaciones endocrino-metabólicas de la obesidad: Hipogonadismo masculino e hígado graso.
11. Hiperlipoproteinemia, resistencia a la insulina y enfermedad aterosclerótica.
12. Inmunidad en las enfermedades metabólicas.
13. Papel de la gestación y lactancia en el desarrollo de enfermedades metabólicas.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
Plataforma de Biobanco y Biomodelos Animales y 3D de Málaga. 2021-2023 Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades.
Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades.
Plataforma de Biobanco y Biomodelos Animales y 3D de Málaga
2021
Avances en medicina de precisión de la obesidad: Análisis multiómico y dinámico para el descubrimiento y validación de biomarcadores predictores de pérdida de peso tras intervención en personas de alto riesgo
Instituto de Salud Carlos III (ISCIII)
Proyectos de Investigación de Medicina Personalizada de Precisión de la Acción Estratégica en Salud 2017-2020
2022
PT20/00101 Plataforma Biobanco y Biomodelos
Instituto de Salud Carlos III
.
2020
Papel de los cuerpos cetónicos y la microbiota en el abordaje dietético de la obesidad. Proyecto secundario: Impacto de la obesidad y sus comorbilidades en el pronóstico y evolución de la enfermedad COVID-19
Consejería de Salud y Familias
.
2020
Molecular Genetics
Ministry of Science, Research and Technology (Islamic Republic)
.
2020
Solicitud para el refuerzo anual de la actividad investigadora en las unidades asistenciales del servicio andaluz de Salud (SAS)
Servicio Andaluz de Salud (SAS)
.
2020
Contratos Río Ortega 2020 Miiguel Damas Fuentes. Jefe de Grupo: Francisco J. Tinahones Madueño
Instituto de Salud Carlos III
.
2020
Contrato Predoctoral. Candidato: Hatim Boughanem Lakhal, Jefe de Grupo: Manuel Macías González
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
Contratos Miguel Servet 2020 Almudena Ortega Gomez
Instituto de Salud Carlos III
.
2020
00040 Contratos Juan Rodes 2020 Maria Molina Vega
Instituto de Salud Carlos III
.
2020
Contratos Miguel Servet 2020 Carolina Gutierrez Repiso
Instituto de Salud Carlos III
.
2020
S1574165220315 LINEA DE AYUDAS PARA LA CAPTACIÓN, INCORPORACIÓN Y MOVILIDAD DE CAPITAL HUMANO DE I+D+i FRANCISCO TINAHONES MADUEÑO.
Consejería de Economía, Conocimiento, Empresas y Universidad
.
2019
ECT2019-000575 Promoción y coordinación de participación en H2020 del instituto de investigación biomédica de Málaga(IBIMA) y centros del sistema sanitario de Málaga
Agencia Estatal de Investigación
.
2019
A1-0052-2019 SOLICITUD PARA EL REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)
Servicio Andaluz de Salud (SAS)
.
2019
RB-0001-2019 RENOVACIÓN ACCION B CONVOCATORIA 2014 EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)
Servicio Andaluz de Salud (SAS)
.
2019
PI19/00507 Fitness mitocondrial diana para la terapia contra la prediabetes IP MORA MURRI PIERRI
ISCIII
.
2019
PI-0419-2019. Efecto de metformina sobre microbiota, inflamación, estrés oxidativo y su potenciales beneficios sobre la función célula β a través de cambios epigenéticos en diabetes gestacional.
Consejería de Salud y Familias
.
2019
JR19-00054 Contratos Juan Rodes 2019
ISCIII
.
2019
IJC2018-037733- IAYUDAS JUAN DE LA CIERVA – INCORPORACIÓN 2018
Agencia Estatal de Investigación
.
2019
ML4Microbiome – Statistical and machine learning techniques in human microbiome studies
Comisión Europea
.
2019
B-0001-2019 Acciones para el refuerzo con recursos humanos de la actividad investigadora en las unidades de Gestión clínica del Servicio Andaluz de Salud 2019.Acción B clínicos investigadores.
SAS
.
2019
FI19-00178 Contratos predoctorales de formación en investigación en salud
ISCIII
.
2019
MOV19-002 MicroARNs: modulación de la mitofagia en adipocitos
Instituto de Investigación Biomédica de Málaga (IBIMA)
.
2019
CAS19-00342 Estancia movilidad en el extranjero José Castillejo para jóvenes doctores 2019
Ministerio de Ciencia e Innovación
.
2019
CD19-00216 Contratos Sara Borrell 2019
ISCIII
.
2019
Albert Renold Travel Fellowship Programme 2019
European Association for the Study of Diabetes
.
2019
Microbiome and methylome relationship before and after a weight loss treatment in liquid biopsia from patients with obesity-related liver disease for the identification of liver risk biomarkers (ONCOHEPATOBESITY-MARK)
CIBEROBN - INSTITUTO DE SALUD CARLOS III
INTERCIBER
2018
CM18-00120 Contratos Río Hortega 2018 Maria Molina Vega Jefe del Grupo: Fernando Cardona Diaz
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA
2018
SED-2018-02 DIFERENCIAS EN MICROBIOTA ENTRE PACIENTES CON DIABETES MELLITUS GESTACIONAL TRATADAS CON INSULINA FRENTE A AQUELLAS TRATADAS CON METFORMINA Y SU POSIBLE PAPEL EN EL CONTROL METABÓLICO, LA INFLAMACIÓN Y LOS RESULTADOS OBSTÉTRICOS Y PERINATALES. IP: María Molina Vega
SOCIEDAD ESPAÑOLA DE DIABETES
AYUDAS SED A PROYECTOS DE INVESTIGACIÓN BÁSICA Y CLÍNICA EN DIABETES DIRIGIDOS POR JÓVENES INVESTIGADORES
2018
A-0033-2018 Acciones A. Intensificación SAS. Refuerzo Anual de la Actividad Investigadora en las Unidades de Gestión Clínica (UGC) del Servicio Andaluz de Salud 2018.Profesionales Propuestos: Francisco Tinahones Madueño
SERVICIO ANDALUZ DE SALUD
ACCIÓN A. REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UGC DEL SAS
2018
B-0033-2014 B-0034-2014 Refuerzo mediante contratos de larga duración de las UGC del SAS, para el desarrollo de programas de investigación, desarrollo e innovación.
SERVICIO ANDALUZ DE SALUD
REFUERZO MEDIANTE CONTRATOS DE LARGA DURACIÓN DE LAS UGC DEL SAS, PARA EL DESARROLLO DE PROGRAMAS DE I
2014
RIC-0539-2018: RED DE ENSAYOS CLÍNICOS EN METABOLISMO: DIABETES, OBESIDAD Y DISLIPEMIA
CONSEJERÍA DE SALUD
PROYECTOS INVESTIGACIÓN CLÍNICA EN RED CON FORTALECIMIENTO DEL CAPITAL HUMANO INVESTIGADOR
2018
PI18/01160 PAPEL DE LOS CUERPOS CETONICOS Y LA MICROBIOTA EN EL ABORDAJE DIETETICO DE LA OBESIDAD
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
PI15/01114 Modificaciones epigenéticas y microbiota en la génesis de la disfunción del tejido adiposo y la resistencia a la insulina.
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2015
FJCI-2016-28173 JC Formacion 2016. Medicina Clínica y epidemiología
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS JUAN DE LA CIERVA FORMACIÓN
2017
PI-0151-2018: Papel de la microbiota intestinal en la patogénesis de la espondiloartritis axial radiográfica.
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
MS17/00133 Miguel Servet Tipo I
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2017
PI-0297-2018: MITOTERAPIA APLICADA A LA OBESIDAD Y SÍNDROME METABÓLICO
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CP17/00133 Mitophagy in Adiposse tissue:getting at the heart of metabolic disorders
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2017
PI18/01175 Efecto de la diabetes gestacional sobre el epigenoma de la madre y de la descendencia en los 1000 primeros días. Identificación de potenciales biomarcadores epigenéticos de riesgo de DM2
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
PI15/01350 Cambios epigenéticos en la evolución del obeso metabólicamente sano. Búsqueda de nuevos biomarcadores. Estudio prospectivo y de intervención.
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2015
CM17/00169 Rio Hortega 2017
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA
2017
PI-0283-2018: Patrón de metilación de ADN circulante como marcador de muerte de célula beta en diabetes gestacional. Búsqueda de biomarcadores de conversión de diabetes gestacional a diabetes tipo 2 en biopsia líquida.
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
RC-0001-2018 Acción C Nicolás Monardes Manuel Macias
SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA
2018
PI18/01399 Nuevo papel en la regulación epigenetica del sistema de la vitamina D y antagonistas de la vía Wnt-Bcatenin en obesidad y sus comorbilidades
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CPII18-00030 Miguel Servet Tipo II 2018 Lourdes Garrido Sánchez
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO II
2018
MS13/00188 MIGUEL SERVET I CONTRATO: Efecto de las LDL oxidadas y anticuerpos anti-LDL oxidada sobre el metabolismo del adipocito y sobre la resistencia a la insulina
INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I
2013
PI-0194-2017 Nuevos Biomarcadores de Respuesta Precoz y Tardía A la Pérdida de Peso Tras la Cirugía Bariátrica
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2017
PI17/01407 Nuevos biomarcadores de respuesta precoz y tardía a la pérdida de peso tras la cirugía bariátrica
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2017
PI14/01306 Papel de las células endoteliales vasculares como mediadoras de la respuesta frente a la dieta
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2014
MS16/00163 Contrato Miguel Servet Tipo I 2016 Isabel Moreno Indias
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2016
MdeOya-001-2017 Definiendo el papel de la microbiota intestinal en los beneficios para la salud reportados por el consumo de cerveza
CENTRO DE INFORMACIÓN CERVEZA Y SALUD
BECAS DE INVESTIGACIÓN MANUEL DE OYA. CERVEZA, SALUD Y NUTRICIÓN
2017
CP16/00163 Proyecto asociado Miguel Servet Tipo I 2016 Isabel Moreno Indias: Through the completely understanding of the mechanisms underlying the link between obesity and gut microbiota
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2016
IJCI-2017-33065 JCI Carolina Gutiérrez Repiso Investigadora Candidata: Carolina Gutiérrez Repiso / Jefe de Grupo: Francisco José Tinahones Madueño Área Científica: Medicina Clínica y Epidemiología
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS JUAN DE LA CIERVA INCORPORACIÓN
2018
PI-0334-2016 Papel de la Microbiota del Estómago y Yeyuno en la Obesidad y Diabetes Tipo 2. Asociación Con la Inflamación, Permeabilidad de la Membrana y Hormonas Gastrointestinales
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
Estudios Clínicos
Seguridad, tolerabilidad, farmacocinética y farmacodinámica de dosis subcutáneas únicas y múltiples de NNC0365-3769 (Mim8) en pacientes sanos y en pacientes con hemofilia A con o sin inhibidores del factor VIII. (FRONTIER 1).
NOVO NORDISK A/S
Fase: II
Ensayo Clínico Comercial
Estudio comparativo de fase IIb, abierto, aleatorizado, doble ciego, controlado con placebo y multicéntrico de la cotadutida en participantes con nefropatía crónica y diabetes mellitus de tipo 2 (CKD).
ASTRAZENECA AB MM
Fase: II
Ensayo Clínico Comercial
Antagonismo del receptor de glucocorticoides en el tratamiento del hipercortisolismo en pacientes con adenomas suprarrenales que secretan cortisol o hiperplasia (GRADIENT): Estudio de fase III, aleatorizado, doble ciego y comparado con placebo sobre la ef.
CORCEPT THERAPEUTICS INCORPORATED
Fase: III
Ensayo Clínico Comercial
Estudio de fase 2, aleatorizado, sin enmascaramiento, con un tratamiento comparativo y grupos paralelos, para evaluar la seguridad y la eficacia de LY3209590 en pacientes con diabetes mellitus de tipo 1 que anteriormente han recibido tratamiento con varia.
LILLY, S.A.U.
Fase: II
Ensayo Clínico Comercial
Comparación del efecto de tirzepatida frente al de dulaglutida sobre los acontecimientos cardiovasculares mayores en pacientes con diabetes de tipo 2 (SURPASS-CVOT).
Lilly, S.A.U
Fase: III
Ensayo Clínico Comercial
Estudio de extensión sin enmascaramiento de la seguridad de relacorilant (CORT125134) en el tratamiento de los signos y síntomas del síndrome de Cushing endógeno.
CORCEPT THERAPEUTICS INCORPORATED
Fase: III
Ensayo Clínico Comercial
I8B-MC-ITSG. Estudio prospectivo, aleatorizado, doble ciego, en el que se comparan LY900014 y Fiasp®, ambos en combinación con insulina basal, en adultos con diabetes de tipo 1PRONTO-Compare
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
FIM-MET-2015-01. Eficacia del tratamiento con metformina en diabetes gestacional no controlada con dieta frente al uso de insulinoterapia.Estudio MeDiGes.
FUNDACION PÚBLICA ANDALUZA PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD FIMABIS
Fase: IV
ENSAYO CLINICO INDEPENDIENTE
FPS-INSUPAR-2015-01. Insulina basal subcutanea versus intravenosa en pacientes diabéticos hospitalizados no criticos que reciben nutricion parental total
FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Fase: IV
ENSAYO CLINICO INDEPENDIENTE
THR-1442-C-480. Estudio en fase 3, aleatorizado, controlado con elemento activo, doble ciego para evaluar los efectos de bexagliflozina en comparación con glimepirida en sujetos con diabetes mellitus tipo 2 que tienen un control glucémico inadecuado con metformina.
THERACOS SUB, LLC
Fase: III
ENSAYO CLINICO COMERCIAL
THR-1442-C-448. Estudio doble ciego, controlado con placebo para evaluar el efecto de los comprimidos de bexagliflozina sobre la hemoglobina A1c en pacientes con diabetes mellitus de tipo 2 e insuficiencia renal moderada
THERACOS SUB, LLC
Fase: III
ENSAYO CLINICO COMERCIAL
NN9924-4221. PIONEER 6 Resultados cardiovasculares. Ensayo para investigar la seguridad cardiovascular de semaglutida oral en sujetos con diabetes tipo 2
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
NN9828-4150. Ensayo clínico demostrativo preliminar, multicéntrico, aleatorizado, doble ciego, doble enmascarado, controlado con placebo y de grupos paralelos en sujetos adultos con diabetes mellitus tipo 1 recién diagnosticada para investigar el efecto de NNC0114-000
NOVO NORDISK A/S
Fase: II
ENSAYO CLINICO COMERCIAL
NN9536-4374. Efecto y seguridad de semaglutida 2,4 mg una vez a la semana en sujetos con sobrepeso u obesidad y diabetes tipo 2
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
NN9535-4386. Efecto de semaglutida una vez a la semana frente a insulin aspart tres veces al día, ambas añadidas a metformina e insulina glargina optimizada (U100), en sujetos con diabetes tipo 2 Ensayo de 52 semanas, multicéntrico, multinacional, abierto, con contro
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
LIRALUNG. Ensayo clínico multicéntrico, aleatorizado, doble ciego, cruzado y controlado con placebo para evaluar el efecto de Liraglutida sobre la función pulmonar de pacientes con diabetes mellitus tipo 2 (Estudio LIRALUNG)
ALBERT LECUBE TORELLO
Fase: IV
ENSAYO CLINICO COMERCIAL
I8B-MC-ITRM. Estudio prospectivo, aleatorizado y doble ciego, en el que se compara LY900014 con la insulina lispro, con un grupo abierto en el que se administra LY900014 posprandial, en combinación con insulina glargina o insulina degludec, en adultos con diabetes de
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
H9X-MC-GBGL. Estudio aleatorizado, doble ciego y con grupos paralelos para evaluar la eficacia y la seguridad de las dosis de dulaglutida en investigación cuando se añaden al tratamiento con metformina en pacientes con diabetes mellitus tipo 2
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
GLP116174. Estudio a largo plazo, aleatorizado, doble ciego, controlado con placebo para determinar el efecto de Albiglutida, cuando se añade al tratamiento hipoglucemiante estándar, sobre eventos cardiovasculares mayores en pacientes con Diabetes Mellitus Tipo2
GLAXOSMITHKLINE, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
GL-GLAT1-3001. Estudio en fase III, abierto, aleatorizado y multicéntrico, para comparar la inmunogenicidad, eficacia y seguridad de la inyección de insulina glargina de Gan & Lee Pharmaceuticals con Lantus® (inyección de insulina glargina) en sujetos adultos con diabet
GAN & LEE PHARMACEUTICALS
Fase: III
ENSAYO CLINICO COMERCIAL
EFC15166. Estudio multicéntrico, aleatorizado, con enmascaramiento doble, de tres grupos paralelos controlados con placebo de 52 semanas de duración para evaluar la eficacia y la seguridad de sotagliflozina en pacientes con diabetes mellitus de tipo 2 e insuficienc
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
EFC14867. Estudio de 26 semanas aleatorizado, doble ciego, controlado, multicéntrico con grupos paralelos para evaluar la eficacia y seguridad de sotagliflozina en comparación con empagliflozina y placebo en pacientes con diabetes de tipo 2 que tienen un control gl
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
EFC13794. Estudio abierto, de 26 semanas de duración, para evaluar la eficacia y seguridad de la combinación en proporción fija de insulina glargina/lixisenatida en adultos con Diabetes Tipo 2 no controlados adecuadamente con un agonista del receptor de GLP-1 y met
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
DRI13940. Estudio en Fase II, Aleatorizado, de Doble Ciego, Controlado con Placebo, de Escalada de Dosis, de 26 Semanas de Duración, para Evaluar la Seguridad y la Eficacia de Estudio en Fase II, Aleatorizado, de Doble Ciego, Controlado con Placebo, de Escalada de
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: II
ENSAYO CLINICO COMERCIAL
D169AC00001. Ensayo Clínico para Evaluar el Efecto de Dapagliflozina sobre el Riesgo de Eventos Renales y Mortalidad Cardiovascular en Pacientes con Enfermedad Renal Crónica.
ASTRAZENECA AB
Fase: III
ENSAYO CLINICO COMERCIAL
BCB109. Ensayo clínico aleatorizado, controlado con placebo, para evaluar los resultados clínicos cardiovasculares tras el tratamiento con Exenatida una vez a la semana en pacientes con Diabetes Mellitus de tipo 2
AMYLIN PHARMACEUTICALS INC.
Fase: III
ENSAYO CLINICO COMERCIAL
28431754DNE3001. Estudio aleatorizado, doble ciego, motivado por los acontecimientos, controlado con placebo y multicéntrico, de los efectos de la canagliflozina en los resultados renales y cardiovasculares en sujetos con diabetes mellitus tipo 2 y nefropatía diabética
JANSSEN-CILAG, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
28431754DIA4003. Ensayo Randomizado, Multicéntrico, Doble ciego, Paralelo, Controlado con Placebo, de los efectos de la Canaglifozina en eventos renales, en sujetos adultos con Diabetes Mellitus Tipo II
JANSSEN-CILAG, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
1218.22. Estudio multicéntrico, internacional, aleatorizado, en grupos paralelos, doble ciego y controlado con placebo sobre seguridad cardiovascular y resultados microvasculares renales con linagliptina, administrada en dosis de 5 mg una vez al día en pacientes c
BOEHRINGER INGELHEIM ESPAÑA, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
I8B-MC-ITRN. Protocolo I8B-MC-ITRNEstudio prospectivo, aleatorizado y doble ciego en el que se compara LY900014 con insulina lispro, ambos en combinación con insulina glargina o insulina degludec, en adultos con diabetes de tipo 2 PRONTO-T2D
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
EFC14837. Estudio multicéntrico, aleatorizado, con enmascaramiento doble, de tres grupos paralelos controlados con placebo de 52 semanas de duración para evaluar la eficacia y la seguridad de sotagliflozina en pacientes con diabetes mellitus de tipo 2 e insuficienc
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
Patentes y Tecnologías
Medicina de precisión para el tratamiento de la obesidad
Said Lhamyani
Tinahones Madueño, Francisco José
el Bekay Rizky, Rajaa
Gentile, Adriana Mariel
Tinahones Madueño, Francisco José
el Bekay Rizky, Rajaa
Gentile, Adriana Mariel
Gentile, Adriana Mariel
Kit para pronosticar el riesgo de recidiva en cáncer de mama
Emilio Alba Conejo
Lozano Castro, José
Jerez Aragones, Jose Manuel
Ribelles Entrena, Nuria
Lozano Castro, José
Jerez Aragones, Jose Manuel
Ribelles Entrena, Nuria
Ribelles Entrena, Nuria
Biomarcadores epigenéticos para el diagnóstico y prevención de la evolución de la obesidad
Morcillo Espina, María Sonsoles
Rojo Martinez, Gemma
Linares Pineda, Teresa María
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
Rojo Martinez, Gemma
Linares Pineda, Teresa María
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
González Jiménez, Andrés
Valdés Hernández, Sergio
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
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Gut microbiota of patients with type 2 diabetes and gastrointestinal intolerance to metformin differs in composition and functionality from tolerant patients
Díaz-Perdigones CM, Muñoz-Garach A, Álvarez-Bermúdez MD, Moreno-Indias I, Tinahones FJ Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145():112448
Metformin action over gut microbiota is related to weight and glycemic control in gestational diabetes mellitus: A randomized trial
Molina-Vega M, Picón-César MJ, Gutiérrez-Repiso C, Fernández-Valero A, Lima-Rubio F, et al. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145():112465
25-Hydroxyvitamin D status is associated with interleukin-6 methylation in adipose tissue from patients with colorectal cancer
Boughanem H, Ruiz-Limon P, Crujeiras AB, de Luque V, Tinahones FJ, et al. Food & function 2021 Oct 19;12(20):9620-9631
A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial
Sanllorente A, Soria-Florido MT, Castañer O, Lassale C, Salas-Salvadó J, et al. The American journal of clinical nutrition 2021 Nov 8;114(5):1666-1674
An alcohol-free beer enriched with isomaltulose and a resistant dextrin modulates gut microbiome in subjects with type 2 diabetes mellitus and overweight or obesity: a pilot study
Mateo-Gallego, R; Moreno-Indias, I; Bea, AM; Sanchez-Alcoholado, L; Fumanal, AJ; Quesada-Molina, M; Prieto-Martin, A; Gutierrez-Repiso, C; Civeira, F; Tinahones, FJ FOOD & FUNCTION 2021
An Epigenetic Signature is Associated with Serum 25-Hydroxyvitamin D in Colorectal Cancer Tumors
Boughanem H, Izquierdo AG, Hernández-Alonso P, Arranz-Salas I, Casanueva FF, et al. Molecular nutrition & food research 2021 Sep;65(18):e2100125
Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment
Marcos-Zambrano LJ, Karaduzovic-Hadziabdic K, Loncar Turukalo T, Przymus P, Trajkovik V, et al. Frontiers in microbiology 2021;12():634511
Assessment of price and nutritional quality of gluten-free products versus their analogues with gluten through the algorithm of the nutri-score front-of-package labeling system
de las Heras-Delgado, S; Alias-Guerrero, ADN; Cendra-Duarte, E; Salas-Salvado, J; Vilchez, E; Roger, E; Hernandez-Alonso, P; Babio, N FOOD & FUNCTION 2021
Association between ankle-brachial index and cognitive function in participants in the PREDIMED-Plus study: cross-sectional assessment
López M, Ríos A, Romaguera D, Martínez-González MÁ, Fernández-Aranda F, et al. Revista espanola de cardiologia (English ed.) 2021 Oct;74(10):846-853
Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population
Paz-Graniel, I; Babio, N; Becerra-Tomas, N; Toledo, E; Camacho-Barcia, L; Corella, D; Castaner-Nino, O; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Tinahones, FJ; Fernandez-Aranda, F; Lapetra, J; Pinto, X; Tur, JA; Garcia-Rios, A; Bueno-Cavanillas, A; Gaforio, JJ; Matia-Martin, P; Daimiel, L; Sanchez, VM; Vidal, J; Prieto-Sanchez, L; Ros, E; Razquin, C; Mestres, C; Sorli, JV; Cuenca-Royo, AM; Rios, A; Torres-Collado, L; Vaquero-Luna, J; Perez-Farinos, N; Zulet, MA; Sanchez-Villegas, A; Casas, R; Bernal-Lopez, MR; Santos-Lozano, JM; Corbella, X; Mateos, D; Buil-Cosiales, P; Jimenez-Murcia, S; Fernandez-Carrion, R; Forcano-Gamazo, L; Lopez, M; Sempere-Pascual, MA; Moreno-Rodriguez, A; Gea, A; De la Torre-Fornell, R; Salas-Salvado, J EUROPEAN JOURNAL OF NUTRITION 2021
Blood Hemoglobin Substantially Modulates the Impact of Gender, Morbid Obesity, and Hyperglycemia on COVID-19 Death Risk: A Multicenter Study in Italy and Spain
Mayneris-Perxachs J, Russo MF, Ramos R, de Hollanda A, Arxé AA, et al. Frontiers in endocrinology 2021;12():741248
Editorial: Emerging Roles of the Gut Microbiota in the Pathogenesis of Metabolic Disorders.
Moreno-Indias I, Salgado-Somoza A, El Azzouzi H, Murri M Frontiers in endocrinology 2021;12():736371
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study
Papandreou C, Bulló M, Hernández-Alonso P, Ruiz-Canela M, Li J, et al. Clinical chemistry 2021 Jan 8;67(1):288-297
Cognitive Functioning and Cortical Brain Thickness in Acromegaly Patients: A Pilot study
García-Casares N, Fernández-Andújar M, González-Molero I, Maraver-Selfa S, Gutiérrez-Bedmar M, et al. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2021 Jul 19;36(5):780-790
Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome
Díaz-López A, Paz-Graniel I, Ruiz V, Toledo E, Becerra-Tomás N, et al. Scientific reports 2021 Apr 22;11(1):8719
Dairy consumption, plasma metabolites, and risk of type 2 diabetes
Drouin-Chartier JP, Hernández-Alonso P, Guasch-Ferré M, Ruiz-Canela M, Li J, et al. The American journal of clinical nutrition 2021 Jul 1;114(1):163-174
Dietary folate intake and metabolic syndrome in participants of PREDIMED-Plus study: a cross-sectional study
Navarrete-Munoz, EM; Vioque, J; Toledo, E; Oncina-Canovas, A; Martinez-Gonzalez, MA; Salas-Salvado, J; Corella, D; Fito, M; Romaguera, D; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Tinahones, FJ; Lapetra, J; Pinto, X; Tur, JA; Lopez-Miranda, J; Bueno-Cavanillas, A; Matia-Martin, P; Daimiel, L; Sanchez, VM; Vidal, J; Blanco, AID; Ros, E; Diez-Espino, J; Babio, N; Fernandez-Carrion, R; Castaner, O; Colom, A; Compan-Gabucio, L; Lete, IS; Crespo-Oliva, E; Abete, I; Tomaino, L; Casas, R; Fernandez-Garcia, JC; Santos-Lozano, JM; Sarasa, I; Garcia-Rios, JMA; Martin-Pelaez, S; Ruiz-Canela, M; Diaz-Lopez, A; Martinez-Lacruz, R; Zomeno, MD; Rayo, E; Selles, CG; Canudas, S; Goday, A; Garcia-de-la-Hera, M EUROPEAN JOURNAL OF NUTRITION 2021
Dietary vitamin D intake and colorectal cancer risk: a longitudinal approach within the PREDIMED study
Hernandez-Alonso, P; Canudas, S; Boughanem, H; Toledo, E; Sorli, JV; Estruch, R; Castaner, O; Lapetra, J; Alonso-Gomez, AM; Gutierrez-Bedmar, M; Fiol, M; Serra-Majem, L; Pinto, X; Ros, E; Fernandez-Lazaro, CI; Ramirez-Sabio, JB; Fito, M; Portu-Zapirain, J; Macias-Gonzalez, M; Babio, N; Salas-Salvado, J EUROPEAN JOURNAL OF NUTRITION 2021
Napping, nocturnal sleep and adiposity
Garach, AM; Perez, AMG NUTRICION HOSPITALARIA 2021
Different Weight Loss Intervention Approaches Reveal a Lack of a Common Pattern of Gut Microbiota Changes
Gutiérrez-Repiso C, Molina-Vega M, Bernal-López MR, Garrido-Sánchez L, García-Almeida JM, et al. Journal of personalized medicine 2021 Feb 8;11(2):
Effect of an Intensive Weight-Loss Lifestyle Intervention on Kidney Function: A Randomized Controlled Trial
Diaz-Lopez, A; Becerra-Tomas, N; Ruiz, V; Toledo, E; Babio, N; Corella, D; Fito, M; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Tinahones, FJ; Lapetra, J; Pinto, X; Tur, JA; Lopez-Miranda, J; Ibanez, NC; Delgado-Rodriguez, M; Matia-Martin, P; Daimiel, L; de Paz, JA; Vidal, J; Vazquez, C; Ruiz-Canela, M; Bullo, M; Sorli, JV; Goday, A; Fiol, M; Garcia-de-la-Hera, M; Sierra, LT; Perez-Farinos, N; Zulet, MA; Sanchez-Villegas, A; Sacanella, E; Fernandez-Garcia, JC; Santos-Lozano, JM; Gimenez-Gracia, M; Bibiloni, MD; Diez-Espino, J; Ortega-Azorin, C; Castaner, O; Morey, M; Torres-Collado, L; Sanchez, CS; Munoz, MA; Ros, E; Martinez-Gonzalez, MA; Salas-Salvado, J AMERICAN JOURNAL OF NEPHROLOGY 2021
Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: Exploratory analyses of AWARD-11
Bonora E, Frias JP, Tinahones FJ, Van J, Malik RE, et al. Diabetes, obesity & metabolism 2021 Oct;23(10):2242-2250
Effect on an Oral Nutritional Supplement with beta-Hydroxy-beta-methylbutyrate and Vitamin D on Morphofunctional Aspects, Body Composition, and Phase Angle in Malnourished Patients
Cornejo-Pareja I, Ramirez M, Camprubi-Robles M, Rueda R, Vegas-Aguilar IM, et al. Nutrients 2021 Dec 3;13(12):
Effect on gut microbiota of a 1-y lifestyle intervention with Mediterranean diet compared with energy-reduced Mediterranean diet and physical activity promotion: PREDIMED-Plus Study
Muralidharan J, Moreno-Indias I, Bulló M, Lopez JV, Corella D, et al. The American journal of clinical nutrition 2021 Sep 1;114(3):1148-1158
Effects of Mosquito Microbiota on the Survival Cost and Development Success of Avian Plasmodium
Martínez-de la Puente J, Gutiérrez-López R, Díez-Fernández A, Soriguer RC, Moreno-Indias I, et al. Frontiers in microbiology 2020;11():562220
Epigenetic Biomarkers of Transition from Metabolically Healthy Obesity to Metabolically Unhealthy Obesity Phenotype: A Prospective Study
Gutiérrez-Repiso C, Linares-Pineda TM, Gonzalez-Jimenez A, Aguilar-Lineros F, Valdés S, et al. International journal of molecular sciences 2021 Sep 27;22(19):
Evidence-based recommendations of the Andalusian Group for Nutrition Reflection and Investigation (GARIN) for the management of adult patients with short bowel syndrome
Vílchez-López FJ, Larrán-Escandón L, García Almeida JM, Arraiza Irigoyen C, Irles Rocamora JA, et al. Nutricion hospitalaria 2021 Dec 9;38(6):1287-1303
Factors Related to Weight Loss Maintenance in the Medium-Long Term after Bariatric Surgery: A Review
Cornejo-Pareja I, Molina-Vega M, Gómez-Pérez AM, Damas-Fuentes M, Tinahones FJ Journal of clinical medicine 2021 Apr 16;10(8):
Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial
Domínguez-López I, Marhuenda-Muñoz M, Tresserra-Rimbau A, Hernáez Á, Moreno JJ, et al. Molecular nutrition & food research 2021 Sep;65(17):e2100363
Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance
Castellano-Castillo D, Ramos-Molina B, Oliva-Olivera W, Ocaña-Wilhelmi L, Queipo-Ortuño MI, et al. Biomedicines 2021 Sep 30;9(10):
Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study
Gómez-Martínez C, Babio N, Júlvez J, Becerra-Tomás N, Martínez-González MÁ, et al. Frontiers in endocrinology 2021;12():754347
Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial
Becerra-Tomás N, Ruiz-Canela M, Hernández-Alonso P, Bulló M, Li J, et al. Metabolites 2021 May 11;11(5):
Gut Microbiota Metabolism of Bile Acids Could Contribute to the Bariatric Surgery Improvements in Extreme Obesity
Ocaña-Wilhelmi L, Martín-Núñez GM, Ruiz-Limón P, Alcaide J, García-Fuentes E, et al. Metabolites 2021 Oct 27;11(11):
Gut Microbiota Profile and Changes in Body Weight in Elderly Subjects with Overweight/Obesity and Metabolic Syndrome
Atzeni A, Galié S, Muralidharan J, Babio N, Tinahones FJ, et al. Microorganisms 2021 Feb 10;9(2):
Gut Microbiota: The Missing Link Between Helicobacter pylori Infection and Metabolic Disorders?
Martin-Nuñez GM, Cornejo-Pareja I, Clemente-Postigo M, Tinahones FJ Frontiers in endocrinology 2021;12():639856
Heart Failure in Type 1 Diabetes: A Complication of Concern? A Narrative Review
Gómez-Perez AM, Damas-Fuentes M, Cornejo-Pareja I, Tinahones FJ Journal of clinical medicine 2021 Sep 29;10(19):
Helicobacter pylori Eradication Therapy Affect the Gut Microbiota and Ghrelin Levels
Martín-Núñez GM, Cornejo-Pareja I, Clemente-Postigo M, Tinahones FJ, Moreno-Indias I Frontiers in medicine 2021;8():712908
High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma
Marhuenda-Muñoz M, Rinaldi de Alvarenga JF, Hernáez Á, Tresserra-Rimbau A, Martínez-González MÁ, et al. Antioxidants (Basel, Switzerland) 2021 Mar 17;10(3):
Human adipose tissue-derived stem cell paracrine networks vary according metabolic risk and after TNF alpha-induced death: An analysis at the single-cell level
Oliva-Olivera, W; Castellano-Castillo, D; von Meyenn, F; Cardona, F; Lonnberg, T; Tinahones, FJ METABOLISM-CLINICAL AND EXPERIMENTAL 2021
Impact of Genetic Polymorphism on Response to Therapy in Non-Alcoholic Fatty Liver Disease
Martínez-Montoro JI, Cornejo-Pareja I, Gómez-Pérez AM, Tinahones FJ Nutrients 2021 Nov 15;13(11):
Impact of the Gestational Diabetes Diagnostic Criteria during the Pandemic: An Observational Study
Molina-Vega M, Gutiérrez-Repiso C, Lima-Rubio F, Suárez-Arana M, Linares-Pineda TM, et al. Journal of clinical medicine 2021 Oct 24;10(21):
Influence of Factors Altering Gastric Microbiota on Bariatric Surgery Metabolic Outcomes
Gutiérrez-Repiso C, Moreno-Indias I, Martín-Núñez GM, Ho-Plagaro A, Ocaña-Wilhelmi L, et al. Microbiology spectrum 2021 Dec 22;9(3):e0053521
Influence of Obesity in the miRNome: miR-4454, a Key Regulator of Insulin Response Via Splicing Modulation in Prostate
Herrero-Aguayo, V; Jimenez-Vacas, JM; Saez-Martinez, P; Gomez-Gomez, E; Lopez-Canovas, JL; Garrido-Sanchez, L; Herrera-Martinez, AD; Garcia-Bermejo, L; Macias-Gonzalez, M; Lopez-Miranda, J; Castano, JP; Gahete, MD; Luque, RM JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2021
Iodine Deficiency and Mortality in Spanish Adults: Di@bet.es Study
Maldonado-Araque C, Valdés S, Badía-Guillén R, Lago-Sampedro A, Colomo N, et al. Thyroid : official journal of the American Thyroid Association 2021 Jan;31(1):106-114
Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study
Sánchez E, Lecube A, Bellido D, Monereo S, Malagón MM, et al. Nutrients 2021 Mar 10;13(3):
Lifestyle Modification Improves Insulin Resistance and Carotid Intima-Media Thickness in a Metabolically Healthy Obese Prepubescent Population
Gallardo-Escribano, C; Vargas-Candela, A; Vilches-Perez, A; Munoz-Melero, M; Ruiz-Moreno, MI; Benitez-Porres, J; Romance-Garcia, AR; Rodriguez-Ortega, R; Rosa-Lopez, A; Rosales-Jaime, A; Diaz-Ruiz, J; Tinahones, FJ; Gomez-Huelgas, R; Bernal-Lopez, MR JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 2021
Lifestyle Modification Program on a Metabolically Healthy Elderly Population with Overweight/Obesity, Young-Old vs. Old-Old. CONSEQUENCES of COVID-19 Lockdown in This Program
Cobos-Palacios L, Muñoz-Úbeda M, Ruiz-Moreno MI, Vilches-Perez A, Vargas-Candela A, et al. International journal of environmental research and public health 2021 Nov 13;18(22):
Longitudinal changes in adherence to the portfolio and DASH dietary patterns and cardiometabolic risk factors in the PREDIMED-Plus study
Glenn, AJ; Hernnandez-Alonso, P; Kendall, CWC; Martinez-Gonzalez, MA; Corella, D; Fito, M; Martinez, JA; Alonso-Gomez, AM; Warnberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Celada, SR; Pinto, X; Delgado-Rodriguez, M; Matia-Martin, P; Vidal, J; Mas-Fontao, S; Daimiel, L; Ros, E; Jenkins, DJA; Toledo, E; Sorli, JV; Castaner, O; Abete, I; Rodriguez, AM; Barcelo, OF; Oncina-Canovas, A; Konieczna, J; Garcia-Rios, A; Casas, R; Gomez-Perez, AM; Santos-Lozano, JM; Vazquez-Ruiz, Z; Portoles, O; Schroder, H; Zulet, MA; Eguaras, S; Lete, IS; Zomeno, MD; Sievenpiper, JL; Salas-Salvado, J CLINICAL NUTRITION 2021
Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort
Nishi SK, Babio N, Gómez-Martínez C, Martínez-González MÁ, Ros E, et al. Frontiers in aging neuroscience 2021;13():782067
Metabolomics of the tryptophan-kynurenine degradation pathway and risk of atrial fibrillation and heart failure: potential modification effect of Mediterranean diet
Razquin C, Ruiz-Canela M, Toledo E, Hernández-Alonso P, Clish CB, et al. The American journal of clinical nutrition 2021 Nov 8;114(5):1646-1654
Metformin for gestational diabetes study: metformin vs insulin in gestational diabetes: glycemic control and obstetrical and perinatal outcomes: randomized prospective trial
Picón-César MJ, Molina-Vega M, Suárez-Arana M, González-Mesa E, Sola-Moyano AP, et al. American journal of obstetrics and gynecology 2021 Nov;225(5):517.e1-517.e17
Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease
Guillot-Sestier MV, Araiz AR, Mela V, Gaban AS, O’Neill E, et al. Communications biology 2021 Jun 10;4(1):711
Milk and Dairy Products Intake Is Related to Cognitive Impairment at Baseline in Predimed Plus Trial
Munoz-Garach, A; Cornejo-Pareja, I; Martinez-Gonzalez, MA; Bullo, M; Corella, D; Castaner, O; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Bernal-Lopez, MR; Lapetra, J; Pinto, X; Tur, JA; Lopez-Miranda, J; Bueno-Cavanillas, A; Delgado-Rodriguez, M; Matia-Martin, P; Daimiel, L; Sanchez, VM; Vidal, J; Prieto, L; Ros, E; Fernandez-Aranda, F; Camacho-Barcia, L; Ortega-Azorin, C; Soria, M; Fiol, M; Compan-Gabucio, L; Goicolea-Guemez, L; Perez-Lopez, J; Goni, N; Perez-Cabrera, J; Sacanella, E; Fernandez-Garcia, JC; Miro-Moriano, L; Gimenez-Gracia, M; Razquin, C; Paz-Graniel, I; Guillem, P; Zomeno, MD; Monino, M; Oncina-Canovas, A; Salaverria-Lete, I; Toledo, E; Salas-Salvado, J; Schroder, H; Tinahones, FJ MOLECULAR NUTRITION & FOOD RESEARCH 2021
miR-21 mimic blocks obesity in mice: A novel therapeutic option
Lhamyani S, Gentile AM, Giráldez-Pérez RM, Feijóo-Cuaresma M, Romero-Zerbo SY, et al. Molecular therapy. Nucleic acids 2021 Dec 3;26():401-416
Moderate Consumption of Beer and Its Effects on Cardiovascular and Metabolic Health: An Updated Review of Recent Scientific Evidence
Marcos A, Serra-Majem L, Pérez-Jiménez F, Pascual V, Tinahones FJ, et al. Nutrients 2021 Mar 9;13(3):
Modulation of Telomere Length by Mediterranean Diet, Caloric Restriction, and Exercise: Results from PREDIMED-Plus Study
Fernández de la Puente M, Hernández-Alonso P, Canudas S, Marti A, Fitó M, et al. Antioxidants (Basel, Switzerland) 2021 Oct 12;10(10):
Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs
Arias de la Rosa I, Escudero-Contreras A, Ruiz-Ponce M, Román-Rodríguez C, Pérez-Sánchez C, et al. Frontiers in immunology 2021;12():744022
Morphofunctional assessment of patient’s nutritional status: a global approach
Almeida, JMG; Garcia, CG; Aguilar, IMV; Castaneda, VB; Guerrero, DB NUTRICION HOSPITALARIA 2021
NGS of microRNAs Involved in Cardioprotection Induced by Sevoflurane Compared to Propofol in Myocardial Revascularization Surgery: The ACDHUVV-16 Clinical Trial
Orriach, JLG; Belmonte, JJE; Aliaga, MR; Fernandez, AR; Capitan, MJR; Munoz, GQ; Ponferrada, AR; Torres, JA; Santiago-Fernandez, C; Gonzalez, EM; Navarro, MR; Bautista, R; Maldonado, JG; Garrido-Sanchez, L; Manas, JC CURRENT MEDICINAL CHEMISTRY 2021
Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges
Kuchay MS, Martínez-Montoro JI, Choudhary NS, Fernández-García JC, Ramos-Molina B Biomedicines 2021 Sep 28;9(10):
Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies
Becerra-Tomas, N; Paz-Graniel, I; Hernandez-Alonso, P; Jenkins, DJA; Kendall, CWC; Sievenpiper, JL; Salas-Salvado, J AMERICAN JOURNAL OF CLINICAL NUTRITION 2021
Oxidized LDL Increase the Proinflammatory Profile of Human Visceral Adipocytes Produced by Hypoxia
Santiago-Fernández C, Martín-Reyes F, Tome M, Gutierrez-Repiso C, Fernandez-Garcia D, et al. Biomedicines 2021 Nov 18;9(11):
Physical activity and metabolic syndrome severity among older adults at cardiovascular risk: 1-Year trends
Gallardo-Alfaro L, Bibiloni MDM, Bouzas C, Mascaró CM, Martínez-González MÁ, et al. Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 Sep 22;31(10):2870-2886
Plasma Metabolomic Profiles of Glycemic Index, Glycemic Load, and Carbohydrate Quality Index in the PREDIMED Study
Bulló M, Papandreou C, Ruiz-Canela M, Guasch-Ferré M, Li J, et al. The Journal of nutrition 2021 Jan 4;151(1):50-58
Potential Role and Impact of Peripheral Blood Mononuclear Cells in Radiographic Axial Spondyloarthritis-Associated Endothelial Dysfunction
Ruiz-Limon P, Ladehesa-Pineda ML, Lopez-Medina C, Lopez-Pedrera C, Abalos-Aguilera MC, et al. Diagnostics (Basel, Switzerland) 2021 Jun 4;11(6):
Potential Role of Insulin Growth-Factor-Binding Protein 2 as Therapeutic Target for Obesity-Related Insulin Resistance
Boughanem H, Yubero-Serrano EM, López-Miranda J, Tinahones FJ, Macias-Gonzalez M International journal of molecular sciences 2021 Jan 24;22(3):
Psychological and metabolic risk factors in older adults with a previous history of eating disorder: A cross-sectional study from the Predimed-Plus study
Vintro-Alcaraz, C; Baenas, I; Lozano-Madrid, M; Granero, R; Ruiz-Canela, M; Babio, N; Corella, D; Fito, M; Martinez, JA; Alonso-Gomez, AM; Warnberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Bernal-Lopez, MR; Lapetra, J; Sanchez-Villegas, A; Bueno-Cavanillas, A; Tur, JA; Martin-Sanchez, V; Pinto, X; Delgado-Rodriguez, M; Matia-Martin, P; Vidal, J; Cardenas, JJ; Daimiel, L; Ros, E; Razquin, C; Diaz-Lopez, A; Gonzalez, JI; Forcano, L; Zulet, MD; Bello-Mora, MC; Valenzuela-Guerrero, S; de la Hera, MG; Konieczna, J; Garcia-Rios, A; Casas, R; Gomez-Perez, AM; Garcia-Arellano, A; Bullo, M; Sorli, JV; Cuenca-Royo, A; Abete, I; Salaverria-Lete, I; Basterra-Gortari, FJ; de la Torre, R; Salas-Salvado, J; Fernandez-Aranda, F EUROPEAN EATING DISORDERS REVIEW 2021
Rate of non-invasive follicular thyroid neoplasms with papillary-like nuclear features depends on pathologist’s criteria: a multicentre retrospective Southern European study with prolonged follow-up
Paja M, Zafón C, Iglesias C, Ugalde A, Cameselle-Teijeiro JM, et al. Endocrine 2021 Jul;73(1):131-140
Recovery of parathyroid function in patients with thyroid cancer treated by total thyroidectomy: An analysis of 685 patients with hypoparathyroidism at discharge of surgery
Diez, JJ; Anda, E; Sastre, J; Perez-Corral, B; Alvarez-Escola, C; Manjon, L; Paja, M; Sambo, M; Santiago-Fernandez, P; Blanco-Carrera, C; Galofre, JC; Navarro, E; Zafon, C; Sanz, E; Oleaga, A; Bandres, O; Donnay, S; Megia, A; Picallo, M; Sanchez-Ragnarsson, C; Baena-Nieto, G; Fernandez-Garcia, JC; Lecumberri, B; de la Vega, MS; Romero-Lluch, AR; Iglesias, P ENDOCRINOLOGIA DIABETES Y NUTRICION 2021
Obesity and COVID-19. A necessary position statement
Bretón I, de Hollanda A, Vilarrasa N, Rubio Herrera MA, Lecube A, et al. Endocrinologia, diabetes y nutricion 2021 Oct;68(8):573-576
Shifts in gut microbiota and their metabolites induced by bariatric surgery. Impact of factors shaping gut microbiota on bariatric surgery outcomes
Gutiérrez-Repiso C, Moreno-Indias I, Tinahones FJ Reviews in endocrine & metabolic disorders 2021 Dec;22(4):1137-1156
Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
Moreno-Indias I, Lahti L, Nedyalkova M, Elbere I, Roshchupkin G, et al. Frontiers in microbiology 2021;12():635781
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes
Lacroix M, Linares LK, Rueda-Rincon N, Bloch K, Di Michele M, et al. Nature communications 2021 Dec 2;12(1):7037
Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes
Testa G, Mora-Maltas B, Camacho-Barcia L, Granero R, Lucas I, et al. Nutrients 2021 Dec 10;13(12):
Up-to-date on the evidence linking miRNA-related epitranscriptomic modifications and disease settings. Can these modifications affect cross-kingdom regulation?
Tomé-Carneiro J, de Las Hazas ML, Boughanem H, Böttcher Y, Cayir A, et al. RNA biology 2021 Nov 12;18(sup2):586-599
Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elderly Population with Metabolic Syndrome (PREDIMED-Plus Cohort)
Martinez-Perez C, San-Cristobal R, Guallar-Castillon P, Martínez-González MÁ, Salas-Salvadó J, et al. Nutrients 2021 Jul 20;13(7):
Validity of the energy-restricted Mediterranean Diet Adherence Screener
Schröder H, Zomeño MD, Martínez-González MA, Salas-Salvadó J, Corella D, et al. Clinical nutrition (Edinburgh, Scotland) 2021 Aug;40(8):4971-4979
Variety in fruits and vegetables, diet quality and lifestyle in an older adult mediterranean population
Lopez-Gonzalez, L; Becerra-Tomas, N; Babio, N; Martinez-Gonzalez, MA; Diaz-Lopez, A; Corella, D; Goday, A; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Tinahones, F; Lapetra, J; Pinto, X; Tur, JA; Lopez-Miranda, J; Bueno-Cavanillas, A; Delgado-Rodriguez, M; Matia-Martin, P; Daimiel, L; Alvarez-Alvarez, L; Vidal, J; Vazquez, C; Ros, E; Vazquez-Ruiz, Z; Canudas, S; Fernandez-Carrion, R; Casaner, O; Zulet, MA; Sierra, LT; Bazan, MJA; Garcia, CML; Martin, M; Garcia-Rios, A; Casas, R; Gomez-Perez, AM; Santos-Lozano, JM; Goni, E; Guillem-Saiz, P; Lassale, C; Abete, I; Lete, IS; Eguaras, S; Schroder, H; Salas-Salvado, J CLINICAL NUTRITION 2021
Visceral Adipose Tissue Phospholipid Signature of Insulin Sensitivity and Obesity
Palau-Rodriguez M, Marco-Ramell A, Casas-Agustench P, Tulipani S, Miñarro A, et al. Journal of proteome research 2021 May 7;20(5):2410-2419
Vitamin D Intake and the Risk of Colorectal Cancer: An Updated Meta-Analysis and Systematic Review of Case-Control and Prospective Cohort Studies
Boughanem H, Canudas S, Hernandez-Alonso P, Becerra-Tomás N, Babio N, et al. Cancers 2021 Jun 4;13(11):
A comparison of the nutritional profile and price of gluten-free products and their gluten-containing counterparts available in the Spanish market
Babio N, Lladó Bellette N, Besora-Moreno M, Castillejo G, Guillén N, et al. Nutricion hospitalaria 2020 Aug 27;37(4):814-822
A Humanized Diet Profile May Facilitate Colonization and Immune Stimulation in Human Microbiota-Colonized Mice
Moreno-Indias I, Lundberg R, Krych L, Metzdorff SB, Kot W, et al. Frontiers in microbiology 2020;11():1336
A lower duodenal immune response is associated with an increase of insulin resistance in patients with morbid obesity
Ho-Plagaro A, Santiago-Fernandez C, García-Serrano S, Rodriguez C, Garrido-Sanchez L, et al. International journal of obesity (2005) 2020 Feb;44(2):340-352
Adherence to a priori dietary indexes and baseline prevalence of cardiovascular risk factors in the PREDIMED-Plus randomised trial
Alvarez-Alvarez I, Toledo E, Lecea O, Salas-Salvadó J, Corella D, et al. European journal of nutrition 2020 Apr;59(3):1219-1232
Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study
Bouzas C, Bibiloni MDM, Julibert A, Ruiz-Canela M, Salas-Salvadó J, et al. Nutrients 2020 Jul 16;12(7):
Adipose tissue depot-specific intracellular and extracellular cues contributing to insulin resistance in obese individuals
Guzmán-Ruiz R, Tercero-Alcázar C, Rabanal-Ruiz Y, Díaz-Ruiz A, El Bekay R, et al. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7520-7539
Adiposity is Associated with Decreased Serum 17-Hydroxyprogesterone Levels in Non-Diabetic Obese Men Aged 18-49: A Cross-Sectional Study
Martínez-Montoro JI, Molina-Vega M, Asenjo-Plaza M, García-Ruiz MC, Varea-Marineto E, et al. Journal of clinical medicine 2020 Nov 28;9(12):
Alirocumab efficacy and safety by body mass index: A pooled analysis from 10 Phase 3 ODYSSEY trials
Tinahones FJ, Laufs U, Cariou B, Louie MJ, Yang J, et al. Diabetes & metabolism 2020 Sep;46(4):280-287
Association between dairy product consumption and hyperuricemia in an elderly population with metabolic syndrome
Mena-Sánchez G, Babio N, Becerra-Tomás N, Martínez-González MÁ, Díaz-López A, et al. Nutrition, metabolism, and cardiovascular diseases : NMCD 2020 Feb 10;30(2):214-222
Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study
Fernández-García JC, Muñoz-Garach A, Martínez-González MÁ, Salas-Salvado J, Corella D, et al. Obesity (Silver Spring, Md.) 2020 Mar;28(3):537-543
Association between Serum Vitamin B12 and Global DNA Methylation in Colorectal Cancer Patients
Boughanem H, Hernandez-Alonso P, Tinahones A, Babio N, Salas-Salvadó J, et al. Nutrients 2020 Nov 20;12(11):
Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study
Barrubés L, Babio N, Hernández-Alonso P, Toledo E, Ramírez Sabio JB, et al. Journal of clinical medicine 2020 Apr 23;9(4):
Association between the APOA2 rs3813627 Single Nucleotide Polymorphism and HDL and APOA1 Levels Through BMI
Boughanem H, Bandera-Merchán B, Hernández-Alonso P, Moreno-Morales N, Tinahones FJ, et al. Biomedicines 2020 Feb 27;8(3):
Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer
Boughanem H, Cabrera-Mulero A, Hernández-Alonso P, Clemente-Postigo M, Casanueva FF, et al. Clinical epigenetics 2020 Jun 9;12(1):83
Breast and Gut Microbiota Action Mechanisms in Breast Cancer Pathogenesis and Treatment
Laborda-Illanes A, Sanchez-Alcoholado L, Dominguez-Recio ME, Jimenez-Rodriguez B, Lavado R, et al. Cancers 2020 Aug 31;12(9):
Carbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trial
Martínez-González MA, Fernandez-Lazaro CI, Toledo E, Díaz-López A, Corella D, et al. The American journal of clinical nutrition 2020 Feb 1;111(2):291-306
Change in serum polyamine metabolome pattern after bariatric surgery in obese patients with metabolic syndrome
Ocaña-Wilhelmi L, Cardona F, Garrido-Sanchez L, Fernandez-Garcia D, Tinahones FJ, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2020 Feb;16(2):306-311
Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjogren’s Syndrome
Cano-Ortiz A, Laborda-Illanes A, Plaza-Andrades I, Membrillo Del Pozo A, Villarrubia Cuadrado A, et al. International journal of molecular sciences 2020 Nov 19;21(22):
Coronavirus disease 2019 (COVID-19) and obesity. Impact of obesity and its main comorbidities in the evolution of the disease
Cornejo-Pareja IM, Gómez-Pérez AM, Fernández-García JC, Barahona San Millan R, Aguilera Luque A, et al. European eating disorders review : the journal of the Eating Disorders Association 2020 Nov;28(6):799-815
COVID Isolation Eating Scale (CIES): Analysis of the impact of confinement in eating disorders and obesity-A collaborative international study
Fernández-Aranda F, Munguía L, Mestre-Bach G, Steward T, Etxandi M, et al. European eating disorders review : the journal of the Eating Disorders Association 2020 Nov;28(6):871-883
Cross-sectional association between non-soy legume consumption, serum uric acid and hyperuricemia: the PREDIMED-Plus study
Becerra-Tomás N, Mena-Sánchez G, Díaz-López A, Martínez-González MÁ, Babio N, et al. European journal of nutrition 2020 Aug;59(5):2195-2206
Diagnosis and treatment of thyroid nodules in Spain. Results of a national survey
Gómez-Pérez AM, Fernández-García JC, Iglesias P, Díez JJ, Álvarez-Escolá C, et al. Endocrinologia, diabetes y nutricion 2020 Aug – Sep;67(7):438-445
Diagnosis, treatment, and management of gestational hypothyroidism. The TIROGEST study
Donnay S, Fajardo C, Fernández-García JC, Torres T, Bandrés O, et al. Endocrinologia, diabetes y nutricion 2020 Jan;67(1):36-42
Diet quality and nutrient density in subjects with metabolic syndrome: Influence of socioeconomic status and lifestyle factors. A cross-sectional assessment in the PREDIMED-Plus study
Cano-Ibáñez N, Gea A, Ruiz-Canela M, Corella D, Salas-Salvadó J, et al. Clinical nutrition (Edinburgh, Scotland) 2020 Apr;39(4):1161-1173
Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study
Castro-Barquero S, Tresserra-Rimbau A, Vitelli-Storelli F, Doménech M, Salas-Salvadó J, et al. Nutrients 2020 Mar 4;12(3):
Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial
Bouzas C, Bibiloni MDM, Garcia S, Mateos D, Martínez-González MÁ, et al. Nutrients 2020 Oct 2;12(10):
Differential Microbial Pattern Description in Subjects with Autoimmune-Based Thyroid Diseases: A Pilot Study
Cornejo-Pareja I, Ruiz-Limón P, Gómez-Pérez AM, Molina-Vega M, Moreno-Indias I, et al. Journal of personalized medicine 2020 Oct 26;10(4):
Effect of alirocumab on individuals with type 2 diabetes, high triglycerides, and low high-density lipoprotein cholesterol
Colhoun HM, Leiter LA, Müller-Wieland D, Cariou B, Ray KK, et al. Cardiovascular diabetology 2020 Feb 8;19(1):14
Effect of changes in adherence to Mediterranean diet on nutrient density after 1-year of follow-up: results from the PREDIMED-Plus Study
Cano-Ibáñez N, Bueno-Cavanillas A, Martínez-González MÁ, Salas-Salvadó J, Corella D, et al. European journal of nutrition 2020 Sep;59(6):2395-2409
Effects of a long-term lifestyle intervention on metabolically healthy women with obesity: Metabolite profiles according to weight loss response
Palau-Rodriguez M, Garcia-Aloy M, Miñarro A, Bernal-Lopez MR, Brunius C, et al. Clinical nutrition (Edinburgh, Scotland) 2020 Jan;39(1):215-224
Efficacy and Safety of iGlarLixi, Fixed-Ratio Combination of Insulin Glargine and Lixisenatide, Compared with Basal-Bolus Regimen in Patients with Type 2 Diabetes: Propensity Score Matched Analysis
Tabák ÁG, Anderson J, Aschner P, Liu M, Saremi A, et al. Diabetes therapy : research, treatment and education of diabetes and related disorders 2020 Jan;11(1):305-318
Efficacy of Low-Dose Radioiodine Ablation in Low- and Intermediate-Risk Differentiated Thyroid Cancer: A Retrospective Comparative Analysis
Gómez-Pérez AM, García-Alemán J, Molina-Vega M, Sebastián Ochoa A, Pérez García P, et al. Journal of clinical medicine 2020 Feb 21;9(2):
Energy System Assessment in Survivors of Breast Cancer
Cuesta-Vargas AI, Buchan J, Pajares B, Alba E, Trinidad-Fernández M, et al. Physical therapy 2020 Mar 10;100(3):438-446
Enhanced NETosis generation in radiographic axial spondyloarthritis: utility as biomarker for disease activity and anti-TNF-alpha therapy effectiveness
Ruiz-Limon P, Ladehesa-Pineda ML, Castro-Villegas MDC, Abalos-Aguilera MDC, Lopez-Medina C, et al. Journal of biomedical science 2020 Apr 17;27(1):54
Epigenetic approach in obesity: DNA methylation in a prepubertal population which underwent a lifestyle modification
Gallardo-Escribano C, Buonaiuto V, Ruiz-Moreno MI, Vargas-Candela A, Vilches-Perez A, et al. Clinical epigenetics 2020 Sep 23;12(1):144
Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseases
Castellano-Castillo D, Ramos-Molina B, Cardona F, Queipo-Ortuño MI Obesity reviews : an official journal of the International Association for the Study of Obesity 2020 Nov;21(11):e13054
Expansion of Rare and Harmful Lineages is Associated with Established Rheumatoid Arthritis
Mena-Vázquez N, Ruiz-Limón P, Moreno-Indias I, Manrique-Arija S, Tinahones FJ, et al. Journal of clinical medicine 2020 Apr 7;9(4):
Factors Accounting for Obesity and Its Perception among the Adult Spanish Population: Data from 1,000 Computer-Assisted Telephone Interviews
Lecube A, Sánchez E, Monereo S, Medina-Gómez G, Bellido D, et al. Obesity facts 2020;13(4):322-332
Fish Oil Enriched Intravenous Lipid Emulsions Reduce Triglyceride Levels in Non-Critically Ill Patients with TPN and Type 2 Diabetes. A Post-Hoc Analysis of the INSUPAR Study
Abuín-Fernández J, Tapia-Guerrero MJ, López-Urdiales R, Herranz-Antolín S, García-Almeida JM, et al. Nutrients 2020 May 27;12(6):
GLIM Criteria at Hospital Admission Predict 8-Year All-Cause Mortality in Elderly Patients With Type 2 Diabetes Mellitus: Results From VIDA Study
Sanz-París A, Martín-Palmero A, Gomez-Candela C, García-Almeida JM, Burgos-Pelaez R, et al. JPEN. Journal of parenteral and enteral nutrition 2020 Nov;44(8):1492-1500
GRK2 levels in myeloid cells modulate adipose-liver crosstalk in high fat diet-induced obesity
Vila-Bedmar R, Cruces-Sande M, Arcones AC, Willemen HLDM, Prieto P, et al. Cellular and molecular life sciences : CMLS 2020 Dec;77(23):4957-4976
Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer
Sánchez-Alcoholado L, Ordóñez R, Otero A, Plaza-Andrade I, Laborda-Illanes A, et al. International journal of molecular sciences 2020 Sep 16;21(18):
H. pylori Eradication Treatment Causes Alterations in the Gut Microbiota and Blood Lipid Levels
Martín-Núñez GM, Cornejo-Pareja I, Roca-Rodríguez MDM, Clemente-Postigo M, Cardona F, et al. Frontiers in medicine 2020;7():417
High sleep variability predicts a blunted weight loss response and short sleep duration a reduced decrease in waist circumference in the PREDIMED-Plus Trial
Papandreou C, Bulló M, Díaz-López A, Martínez-González MA, Corella D, et al. International journal of obesity (2005) 2020 Feb;44(2):330-339
Impact of Tumor LINE-1 Methylation Level and Neoadjuvant Treatment and Its Association with Colorectal Cancer Survival
Boughanem H, Martin-Nuñez GM, Torres E, Arranz-Salas I, Alcaide J, et al. Journal of personalized medicine 2020 Nov 11;10(4):
Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies
De la Rosa IA, Perez-Sanchez C, Ruiz-Limon P, Patiño-Trives A, Torres-Granados C, et al. Haematologica 2020 Sep 1;105(9):2250-2261
Incidental Prophylactic Appendectomy Is Associated with a Profound Microbial Dysbiosis in the Long-Term
Sánchez-Alcoholado L, Fernández-García JC, Gutiérrez-Repiso C, Bernal-López MR, Ocaña-Wilhelmi L, et al. Microorganisms 2020 Apr 23;8(4):
Influence of lifestyle factors and staple foods from the Mediterranean diet on non-alcoholic fatty liver disease among older individuals with metabolic syndrome features
Bullón-Vela V, Abete I, Tur JA, Pintó X, Corbella E, et al. Nutrition (Burbank, Los Angeles County, Calif.) 2020 Mar;71():110620
Jejunal Insulin Signalling Is Increased in Morbidly Obese Subjects with High Insulin Resistance and Is Regulated by Insulin and Leptin
Gutierrez-Repiso C, Ho-Plagaro A, Santiago-Fernandez C, Garcia-Serrano S, Rodríguez-Pacheco F, et al. Journal of clinical medicine 2020 Jan 10;9(1):
Ketotherapy as an epigenetic modifier in cancer
Bandera-Merchan B, Boughanem H, Crujeiras AB, Macias-Gonzalez M, Tinahones FJ Reviews in endocrine & metabolic disorders 2020 Dec;21(4):509-519
Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study
Gallardo-Alfaro L, Bibiloni MDM, Mascaró CM, Montemayor S, Ruiz-Canela M, et al. Nutrients 2020 Apr 7;12(4):
Measurement of Serum Testosterone in Nondiabetic Young Obese Men: Comparison of Direct Immunoassay to Liquid Chromatography-Tandem Mass Spectrometry
Martínez-Escribano A, Maroto-García J, Ruiz-Galdón M, Barrios-Rodríguez R, Álvarez-Millán JJ, et al. Biomolecules 2020 Dec 19;10(12):
Mediterranean Diet and Telomere Length: A Systematic Review and Meta-Analysis
Canudas S, Becerra-Tomás N, Hernández-Alonso P, Galié S, Leung C, et al. Advances in nutrition (Bethesda, Md.) 2020 Nov 16;11(6):1544-1554
Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study
Julibert A, Del Mar Bibiloni M, Gallardo-Alfaro L, Abbate M, Martínez-González MÁ, et al. The Journal of nutrition 2020 Dec 10;150(12):3161-3170
Metabolically Healthy Obesity: Presence of Arterial Stiffness in the Prepubescent Population
Ruiz-Moreno MI, Vilches-Perez A, Gallardo-Escribano C, Vargas-Candela A, Lopez-Carmona MD, et al. International journal of environmental research and public health 2020 Sep 24;17(19):
Microbial Signature in Adipose Tissue of Crohn’s Disease Patients
Serena C, Queipo-Ortuño M, Millan M, Sanchez-Alcoholado L, Caro A, et al. Journal of clinical medicine 2020 Jul 31;9(8):
Microbiota insights in Clostridium difficile infection and inflammatory bowel disease
Rodríguez C, Romero E, Garrido-Sanchez L, Alcaín-Martínez G, Andrade RJ, et al. Gut microbes 2020 Nov 9;12(1):1725220
Milk Replacer Supplementation with Docosahexaenoic Acid from Microalgae Does Not Affect Growth and Immune Status in Goat Kids
Moreno-Indias I, Hernández-Castellano LE, Sánchez-Macías D, Morales-delaNuez A, Torres A, et al. Animals : an open access journal from MDPI 2020 Jul 20;10(7):
MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1
Vonhögen IGC, El Azzouzi H, Olieslagers S, Vasilevich A, de Boer J, et al. Cells 2020 Apr 23;9(4):
miRNA/Target Gene Profile of Endothelial Cells Treated with Human Triglyceride-Rich Lipoproteins Obtained after a High-Fat Meal with Extra-Virgin Olive Oil or Sunflower Oil
Santiago-Fernandez C, Martin-Reyes F, Bautista R, Tome M, Gómez-Maldonado J, et al. Molecular nutrition & food research 2020 Sep;64(17):e2000221
Monoamino oxidase alleles correlate with the presence of essential hypertension among hypogonadic patients
Royo JL, Castellano-Castillo D, Ruiz-Galdon M, Molina-Vega M, Cardona F, et al. Molecular genetics & genomic medicine 2020 Jan;8(1):e1040
Mucosa-associated microbiota in the jejunum of patients with morbid obesity: alterations in states of insulin resistance and metformin treatment
Gutiérrez-Repiso C, Moreno-Indias I, Martín-Núñez GM, Ho-Plágaro A, Rodríguez-Cañete A, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2020 Oct;16(10):1575-1585
Nutrient adequacy and diet quality in a Mediterranean population with metabolic syndrome: A cross-sectional study
Bibiloni MDM, Bouzas C, Abbate M, Martínez-González MA, Corella D, et al. Clinical nutrition (Edinburgh, Scotland) 2020 Mar;39(3):853-861
Oleic Acid Protects Against Insulin Resistance by Regulating the Genes Related to the PI3K Signaling Pathway
López-Gómez C, Santiago-Fernández C, García-Serrano S, García-Escobar E, Gutiérrez-Repiso C, et al. Journal of clinical medicine 2020 Aug 12;9(8):
Oxidized LDL Modify the Human Adipocyte Phenotype to an Insulin Resistant, Proinflamatory and Proapoptotic Profile
Santiago-Fernández C, Martin-Reyes F, Tome M, Ocaña-Wilhelmi L, Rivas-Becerra J, et al. Biomolecules 2020 Apr 1;10(4):
Permanent postoperative hypoparathyroidism: an analysis of prevalence and predictive factors for adequacy of control in a cohort of 260 patients
Díez JJ, Anda E, Sastre J, Pérez Corral B, Álvarez-Escolá C, et al. Gland surgery 2020 Oct;9(5):1380-1388
Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial
Daimiel L, Martínez-González MA, Corella D, Salas-Salvadó J, Schröder H, et al. Scientific reports 2020 Feb 26;10(1):3472
Plasma Metabolomics Profiles are Associated with the Amount and Source of Protein Intake: A Metabolomics Approach within the PREDIMED Study
Hernández-Alonso P, Becerra-Tomás N, Papandreou C, Bulló M, Guasch-Ferré M, et al. Molecular nutrition & food research 2020 Jun;64(12):e2000178
Postprandial Apolipoprotein B48 is Associated with Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis
Mena-Vázquez N, Rojas-Gimenez M, Jimenez Nuñez FG, Manrique-Arija S, Rioja J, et al. Journal of clinical medicine 2020 Aug 2;9(8):
Prevalence of and risk factors for erectile dysfunction in young nondiabetic obese men: results from a regional study
Molina-Vega M, Asenjo-Plaza M, Banderas-Donaire MJ, Hernández-Ollero MD, Rodríguez-Moreno S, et al. Asian journal of andrology 2020 Jul-Aug;22(4):372-378
Quantifying the human diet in the crosstalk between nutrition and health by multi-targeted metabolomics of food and microbiota-derived metabolites
González-Domínguez R, Jáuregui O, Mena P, Hanhineva K, Tinahones FJ, et al. International journal of obesity (2005) 2020 Dec;44(12):2372-2381
Randomized 52-week Phase 2 Trial of Albiglutide Versus Placebo in Adult Patients With Newly Diagnosed Type 1 Diabetes
Pozzilli P, Bosi E, Cirkel D, Harris J, Leech N, et al. The Journal of clinical endocrinology and metabolism 2020 Jun 1;105(6):
Recommendations Based on Evidence by the Andalusian Group for Nutrition Reflection and Investigation (GARIN) for the Pre- and Postoperative Management of Patients Undergoing Obesity Surgery
Martínez-Ortega AJ, Olveira G, Pereira-Cunill JL, Arraiza-Irigoyen C, García-Almeida JM, et al. Nutrients 2020 Jul 6;12(7):
Regular insulin added to total parenteral nutrition vs subcutaneous glargine in non-critically ill diabetic inpatients, a multicenter randomized clinical trial: INSUPAR trial
Olveira G, Abuín J, López R, Herranz S, García-Almeida JM, et al. Clinical nutrition (Edinburgh, Scotland) 2020 Feb;39(2):388-394
Relationship between environmental temperature and the diagnosis and treatment of gestational diabetes mellitus: An observational retrospective study
Molina-Vega M, Gutiérrez-Repiso C, Muñoz-Garach A, Lima-Rubio F, Morcillo S, et al. The Science of the total environment 2020 Nov 20;744():140994
Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk
Sánchez-Quesada C, Toledo E, González-Mata G, Ramos-Ballesta MI, Peis JI, et al. Atherosclerosis 2020 Dec;314():48-57
Relationship of visceral adipose tissue with surrogate insulin resistance and liver markers in individuals with metabolic syndrome chronic complications
Bullón-Vela V, Abete I, Tur JA, Konieczna J, Romaguera D, et al. Therapeutic advances in endocrinology and metabolism 2020;11():2042018820958298
Relationship of Zonulin with Serum PCSK9 Levels after a High Fat Load in a Population of Obese Subjects
Molina-Vega M, Castellano-Castillo D, Sánchez-Alcoholado L, Plaza-Andrade I, Perera-Martin G, et al. Biomolecules 2020 May 11;10(5):
Renal and Neurologic Benefit of LevosimendanvsDobutamine in Patients With Low Cardiac Output Syndrome After Cardiac Surgery: Clinical Trial FIM-BGC-2014-01
Guerrero-Orriach JL, Malo-Manso A, Ramirez-Aliaga M, Florez Vela AI, Galán-Ortega M, et al. Frontiers in pharmacology 2020;11():1331
Risk factors differentially associated with non-alcoholic fatty liver disease in males and females with metabolic syndrome
Bullón Vela MV, Abete I, Zulet MLÁ, Tur JA, Pintó X, et al. Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 2020 Feb;112(2):94-100
RISK FACTORS FOR HYPOGLYCEMIA IN INPATIENTS WITH TOTAL PARENTERAL NUTRITION AND TYPE 2 DIABETES: A POST HOC ANALYSIS OF THE INSUPAR STUDY
Olveira G, Abuín J, López R, Herranz S, García-Almeida JM, et al. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2020 Jun 2;26(6):604-611
SEEDO-SEMERGEN consensus document on continuous care of obesity between Primary Care and Specialist Hospital Units 2019
Caixàs A, Villaró M, Arraiza C, Montalvá JC, Lecube A, et al. Medicina clinica 2020 Sep 25;155(6):267.e1-267.e11
The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome
Marcos-Delgado A, Fernández-Villa T, Martínez-González MÁ, Salas-Salvadó J, Corella D, et al. International journal of environmental research and public health 2020 May 25;17(10):
The Role of Autophagy in White Adipose Tissue Function: Implications for Metabolic Health
Clemente-Postigo M, Tinahones A, El Bekay R, Malagón MM, Tinahones FJ Metabolites 2020 Apr 30;10(5):
The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response
Sánchez-Alcoholado L, Ramos-Molina B, Otero A, Laborda-Illanes A, Ordóñez R, et al. Cancers 2020 May 29;12(6):
Urinary Resveratrol Metabolites Output: Differential Associations with Cardiometabolic Markers and Liver Enzymes in House-Dwelling Subjects Featuring Metabolic Syndrome
Bullón-Vela V, Abete I, Zulet MA, Xu Y, Martínez-González MA, et al. Molecules (Basel, Switzerland) 2020 Sep 22;25(18):
Use of glycerol and propylene glycol as additives in heat-treated goat colostrum
Morales-delaNuez A, Hernández-Castellano LE, Moreno-Indias I, Sánchez-Macías D, Argüello A, et al. Journal of dairy science 2020 Mar;103(3):2756-2761
Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery
Alvarez-Bermudez MD, Martin-Reyes F, Ocaña-Wilhelmi L, Moreno-Ruiz FJ, Torres JA, et al. Journal of clinical medicine 2020 Nov 2;9(11):
ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet
Lorenzo PM, Izquierdo AG, Diaz-Lagares A, Carreira MC, Macias-Gonzalez M, et al. Frontiers in endocrinology 2020;11():245
A New Perspective on the Health Benefits of Moderate Beer Consumption: Involvement of the Gut Microbiota
Quesada-Molina M, Muñoz-Garach A, Tinahones FJ, Moreno-Indias I Metabolites 2019 Nov 9;9(11):
A Pilot Study of Serum Sphingomyelin Dynamics in Subjects with Severe Obesity and Non-alcoholic Steatohepatitis after Sleeve Gastrectomy
Ramos-Molina B, Castellano-Castillo D, Pastor O, Ocaña-Wilhelmi L, Fernández-García D, et al. Obesity surgery 2019 Mar;29(3):983-989
Adherence to an Energy-restricted Mediterranean Diet Score and Prevalence of Cardiovascular Risk Factors in the PREDIMED-Plus: A Cross-sectional Study
Álvarez-Álvarez I, Martínez-González MÁ, Sánchez-Tainta A, Corella D, Díaz-López A, et al. Revista espanola de cardiologia (English ed.) 2019 Nov;72(11):925-934
Alirocumab therapy in individuals with type 2 diabetes mellitus and atherosclerotic cardiovascular disease: analysis of the ODYSSEY DM-DYSLIPIDEMIA and DM-INSULIN studies
Ray KK, Del Prato S, Müller-Wieland D, Cariou B, Colhoun HM, et al. Cardiovascular diabetology 2019 Nov 9;18(1):149
Altered Adipose Tissue DNA Methylation Status in Metabolic Syndrome: Relationships Between Global DNA Methylation and Specific Methylation at Adipogenic, Lipid Metabolism and Inflammatory Candidate Genes and Metabolic Variables
Castellano-Castillo D, Moreno-Indias I, Sanchez-Alcoholado L, Ramos-Molina B, Alcaide-Torres J, et al. Journal of clinical medicine 2019 Jan 13;8(1):
Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients
Castellano-Castillo D, Morcillo S, Crujeiras AB, Sánchez-Alcoholado L, Clemente-Postigo M, et al. BMC cancer 2019 Jan 21;19(1):93
Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex
Tresserra-Rimbau A, Castro-Barquero S, Vitelli-Storelli F, Becerra-Tomas N, Vázquez-Ruiz Z, et al. Antioxidants (Basel, Switzerland) 2019 Nov 8;8(11):
Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin’s putative role as a mediator of decision-making
Paslakis G, Agüera Z, Granero R, Sánchez I, Riesco N, et al. Molecular and cellular endocrinology 2019 Nov 1;497():110441
Cross-sectional, Primary Care-Based Study of the Prevalence of Hypoandrogenemia in Nondiabetic Young Men with Obesity
Molina-Vega M, Asenjo-Plaza M, García-Ruiz MC, Varea-Marineto E, Casal-Nievas N, et al. Obesity (Silver Spring, Md.) 2019 Oct;27(10):1584-1590
Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function
Ortega FJ, Moreno-Navarrete JM, Mercader JM, Gómez-Serrano M, García-Santos E, et al. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Aug;33(8):9656-9671
Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional Analysis
Cano-Ibáñez N, Gea A, Martínez-González MA, Salas-Salvadó J, Corella D, et al. Nutrients 2019 Apr 26;11(5):
Document on a comprehensive approach to type 2 diabetes mellitus
Reyes-García R, Moreno-Pérez Ó, Tejera-Pérez C, Fernández-García D, Bellido-Castañeda V, et al. Endocrinologia, diabetes y nutricion 2019 Aug – Sep;66(7):443-458
Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial
Salas-Salvadó J, Díaz-López A, Ruiz-Canela M, Basora J, Fitó M, et al. Diabetes care 2019 May;42(5):777-788
Effect of a Nutritional and Behavioral Intervention on Energy-Reduced Mediterranean Diet Adherence Among Patients With Metabolic Syndrome: Interim Analysis of the PREDIMED-Plus Randomized Clinical Trial
Sayón-Orea C, Razquin C, Bulló M, Corella D, Fitó M, et al. JAMA 2019 Oct 15;322(15):1486-1499
Effect of Synbiotic Supplementation in a Very-Low-Calorie Ketogenic Diet on Weight Loss Achievement and Gut Microbiota: A Randomized Controlled Pilot Study
Gutiérrez-Repiso C, Hernández-García C, García-Almeida JM, Bellido D, Martín-Núñez GM, et al. Molecular nutrition & food research 2019 Oct;63(19):e1900167
Effect of Telephone-Delivered Interventions on Glycemic Control in Type 2 Diabetes Treated with Glargine Insulin
Bellido V, Bellido D, Tejera C, Carral F, Goicolea I, et al. Telemedicine journal and e-health : the official journal of the American Telemedicine Association 2019 Jun;25(6):471-476
Effects of SHBG rs1799941 Polymorphism on Free Testosterone Levels and Hypogonadism Risk in Young Non-Diabetic Obese Males
Castellano-Castillo D, Royo JL, Martínez-Escribano A, Sánchez-Alcoholado L, Molina-Vega M, et al. Journal of clinical medicine 2019 Jul 31;8(8):
Epigenetic Influences in the Obesity/Colorectal Cancer Axis: A Novel Theragnostic Avenue
Ayers D, Boughanem H, Macías-González M Journal of oncology 2019;2019():7406078
Gender-Related Differences on Polyamine Metabolome in Liquid Biopsies by a Simple and Sensitive Two-Step Liquid-Liquid Extraction and LC-MS/MS.
Samarra I, Ramos-Molina B, Queipo-Ortuño MI, Tinahones FJ, Arola L, et al. Biomolecules 2019 Nov 26;9(12):
Gut microbiota adaptation after weight loss by Roux-en-Y gastric bypass or sleeve gastrectomy bariatric surgeries
Sánchez-Alcoholado L, Gutiérrez-Repiso C, Gómez-Pérez AM, García-Fuentes E, Tinahones FJ, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2019 Nov;15(11):1888-1895
Gut Microbiota Composition Is Associated With the Global DNA Methylation Pattern in Obesity
Ramos-Molina B, Sánchez-Alcoholado L, Cabrera-Mulero A, Lopez-Dominguez R, Carmona-Saez P, et al. Frontiers in genetics 2019;10():613
Gut microbiota specific signatures are related t o the successful rate of bariatric surgery
Gutiérrez-Repiso C, Moreno-Indias I, de Hollanda A, Martín-Núñez GM, Vidal J, et al. American journal of translational research 2019;11(2):942-952
H. pylori Eradication Treatment Alters Gut Microbiota and GLP-1 Secretion in Humans
Cornejo-Pareja I, Martín-Núñez GM, Roca-Rodríguez MM, Cardona F, Coin-Aragüez L, et al. Journal of clinical medicine 2019 Apr 4;8(4):
H. pylori eradication with antibiotic treatment causes changes in glucose homeostasis related to modifications in the gut microbiota
Martín-Núñez GM, Cornejo-Pareja I, Coin-Aragüez L, Roca-Rodríguez MDM, Muñoz-Garach A, et al. PloS one 2019;14(3):e0213548
How often patients on insulin therapy measure postprandial glycemia and modify insulin doses accordingly? From an on-line survey in insulin-treated diabetes patients in Spain
Lecumberri Pascual E, Tejera Pérez C, Muñoz-Garach A, Javier Ampudia-Blasco F Diabetes research and clinical practice 2019 Aug;154():43-51
Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
Castellano-Castillo D, Denechaud PD, Fajas L, Moreno-Indias I, Oliva-Olivera W, et al. PloS one 2019;14(4):e0215083
Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis
Crujeiras AB, Morcillo S, Diaz-Lagares A, Sandoval J, Castellano-Castillo D, et al. International journal of obesity (2005) 2019 Jan;43(1):176-188
Impact of Intensive Lifestyle Modification on Levels of Adipokines and Inflammatory Biomarkers in Metabolically Healthy Obese Women
Gomez-Huelgas R, Ruiz-Nava J, Santamaria-Fernandez S, Vargas-Candela A, Alarcon-Martin AV, et al. Mediators of inflammation 2019;2019():4165260
Importance of gut microbiota in obesity
Cornejo-Pareja I, Muñoz-Garach A, Clemente-Postigo M, Tinahones FJ European journal of clinical nutrition 2019 Jul;72(Suppl 1):26-37
Increased PON lactonase activity in morbidly obese patients is associated with impaired lipid profile
Alaminos-Castillo MÁ, Ho-Plagaro A, García-Serrano S, Santiago-Fernandez C, Rodríguez-Pacheco F, et al. International journal of clinical practice 2019 Jun;73(6):e13315
Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study.
Galmes-Panades AM, Varela-Mato V, Konieczna J, Wärnberg J, Martínez-González MÁ, et al. The international journal of behavioral nutrition and physical activity 2019 Dec 23;16(1):137
Keto microbiota: A powerful contributor to host disease recovery
Cabrera-Mulero A, Tinahones A, Bandera B, Moreno-Indias I, Macías-González M, et al. Reviews in endocrine & metabolic disorders 2019 Dec;20(4):415-425
Lifestyle factors modulate postprandial hypertriglyceridemia: From the CORDIOPREV study
Leon-Acuña A, Torres-Peña JD, Alcala-Diaz JF, Vals-Delgado C, Roncero-Ramos I, et al. Atherosclerosis 2019 Nov;290():118-124
Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome
Papandreou C, Díaz-López A, Babio N, Martínez-González MA, Bulló M, et al. Journal of clinical medicine 2019 Jul 19;8(7):
Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study
Corina A, Rangel-Zúñiga OA, Jiménez-Lucena R, Alcalá-Díaz JF, Quintana-Navarro G, et al. The journals of gerontology. Series A, Biological sciences and medical sciences 2019 May 16;74(6):770-777
Metabolic and Endocrine Consequences of Bariatric Surgery
Cornejo-Pareja I, Clemente-Postigo M, Tinahones FJ Frontiers in endocrinology 2019;10():626
Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity
Clemente-Postigo M, Oliva-Olivera W, Coin-Aragüez L, Ramos-Molina B, Giraldez-Perez RM, et al. American journal of physiology. Endocrinology and metabolism 2019 Feb 1;316(2):E319-E332
miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes
Gentile AM, Lhamyani S, Coín-Aragüez L, Clemente-Postigo M, Oliva Olivera W, et al. Obesity (Silver Spring, Md.) 2019 Feb;27(2):245-254
Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis
Ruiz-Limon P, Ortega-Castro R, Barbarroja N, Perez-Sanchez C, Jamin C, et al. Frontiers in immunology 2019;10():1111
New molecular biomarkers in differentiated thyroid carcinoma: Impact of miR-146, miR-221 and miR-222 levels in the evolution of the disease
Gómez-Pérez AM, Cornejo Pareja IM, García Alemán J, Coín Aragüez L, Sebastián Ochoa A, et al. Clinical endocrinology 2019 Jul;91(1):187-194
Novel SFRP2 DNA Methylation Profile Following Neoadjuvant Therapy in Colorectal Cancer Patients with Different Grades of BMI
Cabrera-Mulero A, Crujeiras AB, Izquierdo AG, Torres E, Ayers D, et al. Journal of clinical medicine 2019 Jul 17;8(7):
Nut Consumptions as a Marker of Higher Diet Quality in a Mediterranean Population at High Cardiovascular Risk
Bibiloni MDM, Julibert A, Bouzas C, Martínez-González MA, Corella D, et al. Nutrients 2019 Mar 30;11(4):
On the Use of Buffy or Whole Blood for Obtaining DNA of High Quality and Functionality: What Is the Best Option?
Ferro P, Ortega-Pinazo J, Martínez B, Jiménez Á, Gómez-Zumaquero JM, et al. Biopreservation and biobanking 2019 Dec;17(6):577-582
Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes
Santiago-Fernández C, Pérez-Belmonte LM, Millán-Gómez M, Moreno-Santos I, Carrasco-Chinchilla F, et al. Journal of translational medicine 2019 Mar 20;17(1):95
Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge
Mantilla-Escalante DC, López de Las Hazas MC, Gil-Zamorano J, Del Pozo-Acebo L, Crespo MC, et al. Nutrients 2019 Jun 13;11(6):
Prevalence of postprandial hyperglycaemia in basal insulin-treated patients with type 2 diabetes mellitus with controlled fasting glycaemia and elevated glycosylated haemoglobin
Tinahones FJ, Molina-Vega M, Parra-Barona J, Flores-Le Roux J, Gómez-Huelgas R Diabetology & metabolic syndrome 2019;11():59
Recommendations of the GARIN group for dietary managing of patient with chronic kidney disease
Alhambra Expósito MR, Molina Puerta MJ, Olveira G, Arraiza Irigoyen C, Fernández Soto M, et al. Nutricion hospitalaria 2019 Mar 7;36(1):183-217
Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa
Steward T, Mestre-Bach G, Granero R, Sánchez I, Riesco N, et al. Scientific reports 2019 May 27;9(1):7910
Role of epicardial adipose tissue NPR-C in acute coronary syndrome
Moreno-Santos I, Macías-González M, Porras-Martín C, Castellano-Castillo D, Sánchez-Espín G, et al. Atherosclerosis 2019 Jul;286():79-87
Sheep and goats raised in mixed flocks have diverse immune status around parturition
Hernández-Castellano LE, Moreno-Indias I, Sánchez-Macías D, Morales-delaNuez A, Torres A, et al. Journal of dairy science 2019 Sep;102(9):8478-8485
Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing
Lützhøft DO, Sánchez-Alcoholado L, Tougaard P, Junker Mentzel CM, Kot W, et al. Research in veterinary science 2019 Oct;126():227-232
Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
Papandreou C, Babio N, Díaz-López A, Martínez-González MÁ, Becerra-Tomas N, et al. Nutrients 2019 Apr 1;11(4):
The Antagonist Effect of Arachidonic Acid on GLUT4 Gene Expression by Nuclear Receptor Type II Regulation
Moreno-Santos I, Garcia-Serrano S, Boughanem H, Garrido-Sanchez L, Tinahones FJ, et al. International journal of molecular sciences 2019 Feb 22;20(4):
The Expression/Methylation Profile of Adipogenic and Inflammatory Transcription Factors in Adipose Tissue Are Linked to Obesity-Related Colorectal Cancer
Boughanem H, Cabrera-Mulero A, Hernández-Alonso P, Bandera-Merchán B, Tinahones A, et al. Cancers 2019 Oct 24;11(11):
The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-beta treatment in a murine model of multiple sclerosis
Melero-Jerez C, Suardíaz M, Lebrón-Galán R, Marín-Bañasco C, Oliver-Martos B, et al. Neurobiology of disease 2019 Jul;127():13-31
Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
Julibert A, Bibiloni MDM, Bouzas C, Martínez-González MÁ, Salas-Salvadó J, et al. Nutrients 2019 Jun 29;11(7):
Transcriptional Analysis of FOXO1, C/EBP-alpha and PPAR-gamma 2 Genes and Their Association with Obesity-Related Insulin Resistance
Boughanem H, Cabrera-Mulero A, Millán-Gómez M, Garrido-Sánchez L, Cardona F, et al. Genes 2019 Sep 12;10(9):
Trends in Diabetes-Related Potentially Preventable Hospitalizations in Adult Population in Spain, 1997-2015: A Nation-Wide Population-Based Study
Gómez-Huelgas R, Lara-Rojas CM, López-Carmona MD, Jansen-Chaparro S, Barba R, et al. Journal of clinical medicine 2019 Apr 11;8(4):
Type 2 Diabetes Is Associated with a Different Pattern of Serum Polyamines: A Case-Control Study from the PREDIMED-Plus Trial
Fernandez-Garcia JC, Delpino-Rius A, Samarra I, Castellano-Castillo D, Muñoz-Garach A, et al. Journal of clinical medicine 2019 Jan 10;8(1):
Vitamin D Status, Calcium Intake and Risk of Developing Type 2 Diabetes: An Unresolved Issue
Muñoz-Garach A, García-Fontana B, Muñoz-Torres M Nutrients 2019 Mar 16;11(3):
A new nutritional approach. Assessment of the patient’s nutritional status: function and body composition
Almeida, JMG; Garcia, CG; Castaneda, VB; Guerrero, DB NUTRICION HOSPITALARIA 2018
Adipose tissue inflammation and VDR expression and methylation in colorectal cancer
Castellano-Castillo D, Morcillo S, Clemente-Postigo M, Crujeiras AB, Fernandez-García JC, et al. Clinical epigenetics 2018;10():60
Adipose Tissue LPL Methylation is Associated with Triglyceride Concentrations in the Metabolic Syndrome
Castellano-Castillo D, Moreno-Indias I, Fernández-García JC, Alcaide-Torres J, Moreno-Santos I, et al. Clinical chemistry 2018 Jan;64(1):210-218
Alirocumab safety in people with and without diabetes mellitus: pooled data from 14 ODYSSEY trials
Leiter LA, Tinahones FJ, Karalis DG, Bujas-Bobanovic M, Letierce A, et al. Diabetic medicine : a journal of the British Diabetic Association 2018 Dec;35(12):1742-1751
Alirocumab vs usual lipid-lowering care as add-on to statin therapy in individuals with type 2 diabetes and mixed dyslipidaemia: The ODYSSEY DM-DYSLIPIDEMIA randomized trial
Ray KK, Leiter LA, Müller-Wieland D, Cariou B, Colhoun HM, et al. Diabetes, obesity & metabolism 2018 Jun;20(6):1479-1489
Characterization of Metabolomic Profile Associated with Metabolic Improvement after Bariatric Surgery in Subjects with Morbid Obesity
Palau-Rodriguez M, Tulipani S, Marco-Ramell A, Miñarro A, Jauregui O, et al. Journal of proteome research 2018 Aug 3;17(8):2704-2714
Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue
Castellano-Castillo D, Denechaud PD, Moreno-Indias I, Tinahones F, Fajas L, et al. PloS one 2018;13(2):e0192314
Circulating Tumor Cells as a Biomarker of Survival and Response to Radium-223 Therapy: Experience in a Cohort of Patients With Metastatic Castration-Resistant Prostate Cancer
Carles J, Castellano D, Méndez-Vidal MJ, Mellado B, Saez MI, et al. Clinical genitourinary cancer 2018 Dec;16(6):e1133-e1139
Complement Factor C3 Methylation and mRNA Expression Is Associated to BMI and Insulin Resistance in Obesity
Castellano-Castillo D, Moreno-Indias I, Fernandez-Garcia JC, Clemente-Postigo M, Castro-Cabezas M, et al. Genes 2018 Aug 13;9(8):
Cross-sectional associations of objectively-measured sleep characteristics with obesity and type 2 diabetes in the PREDIMED-Plus trial
Rosique-Esteban N, Papandreou C, Romaguera D, Warnberg J, Corella D, et al. Sleep 2018 Dec 1;41(12):
Decreased blood pressure is related to changes in NF-kB promoter methylation levels after bariatric surgery
Macías-González M, Martín-Núñez GM, Garrido-Sánchez L, García-Fuentes E, Tinahones FJ, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2018 Sep;14(9):1327-1334
Decreased GPIHBP1 protein levels in visceral adipose tissue partly underlie the hypertriglyceridemic phenotype in insulin resistance
Surendran RP, Udayyapan SD, Clemente-Postigo M, Havik SR, Schimmel AWM, et al. PloS one 2018;13(11):e0205858
Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study
Cano-Ibáñez N, Bueno-Cavanillas A, Martínez-González MA, Corella D, Salas-Salvadó J, et al. Nutrients 2018 Nov 4;10(11):
Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia
Oliva-Olivera W, Coín-Aragüez L, Lhamyani S, Salas J, Gentile AM, et al. Journal of tissue engineering and regenerative medicine 2018 Mar;12(3):e1772-e1784
Differential effects of restrictive and malabsorptive bariatric surgery procedures on the serum lipidome in obese subjects.
Ramos-Molina B, Castellano-Castillo D, Alcaide-Torres J, Pastor Ó, de Luna Díaz R, et al. Journal of clinical lipidology 2018 Nov – Dec;12(6):1502-1512
Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial
Ludvik B, Frías JP, Tinahones FJ, Wainstein J, Jiang H, et al. The lancet. Diabetes & endocrinology 2018 May;6(5):370-381
Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial
Schröder H, Cárdenas-Fuentes G, Martínez-González MA, Corella D, Vioque J, et al. The international journal of behavioral nutrition and physical activity 2018 Nov 13;15(1):110
Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota
Serena C, Ceperuelo-Mallafré V, Keiran N, Queipo-Ortuño MI, Bernal R, et al. The ISME journal 2018 Jun;12(7):1642-1657
Fermented dairy products, diet quality, and cardio-metabolic profile of a Mediterranean cohort at high cardiovascular risk
Mena-Sánchez G, Babio N, Martínez-González MÁ, Corella D, Schröder H, et al. Nutrition, metabolism, and cardiovascular diseases : NMCD 2018 Oct;28(10):1002-1011
Gut Microbiota Differs in Composition and Functionality Between Children With Type 1 Diabetes and MODY2 and Healthy Control Subjects: A Case-Control Study
Leiva-Gea I, Sánchez-Alcoholado L, Martín-Tejedor B, Castellano-Castillo D, Moreno-Indias I, et al. Diabetes care 2018 Nov;41(11):2385-2395
Hyperphagia and Obesity in Prader-Willi Syndrome: PCSK1 Deficiency and Beyond?
Ramos-Molina B, Molina-Vega M, Fernández-García JC, Creemers JW Genes 2018 Jun 7;9(6):
Impact in Plasma Metabolome as Effect of Lifestyle Intervention for Weight-Loss Reveals Metabolic Benefits in Metabolically Healthy Obese Women
Almanza-Aguilera E, Brunius C, Bernal-Lopez MR, Garcia-Aloy M, Madrid-Gambin F, et al. Journal of proteome research 2018 Aug 3;17(8):2600-2610
Implications of the Mediterranean diet and physical exercise on the lipid profile of metabolically healthy obese women as measured by nuclear magnetic resonance spectroscopy (H-1 NMR)
Rodriguez-Garcia E, Ruiz-Nava J, Santamaria-Fernandez S, Fernandez-Garcia JC, Vargas-Candela A, et al. Chemistry and physics of lipids 2018 Jul;213():68-75
Inflammatory gene expression in adipose tissue according to diagnosis of anxiety and mood disorders in obese and non-obese subjects
Coín-Aragüez L, Pavón FJ, Contreras A, Gentile AM, Lhamyani S, et al. Scientific reports 2018 Nov 30;8(1):17518
Involvement of acetyl-CoA-producing enzymes in the deterioration of the functional potential of adipose-derived multipotent cells from subjects with metabolic syndrome.
Oliva-Olivera W, Lhamyani S, Coín-Aragüez L, Alcaide-Torres J, Cardona F, et al. Metabolism: clinical and experimental 2018 Nov;88():12-21
Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study
Maldonado-Araque C, Valdés S, Lago-Sampedro A, Lillo-Muñoz JA, Garcia-Fuentes E, et al. Scientific reports 2018 Apr 26;8(1):6571
Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial
Galilea-Zabalza I, Buil-Cosiales P, Salas-Salvadó J, Toledo E, Ortega-Azorín C, et al. PloS one 2018;13(6):e0198974
Mediterranean diet improves endothelial function in patients with diabetes and prediabetes: A report from the CORDIOPREV study
Torres-Peña JD, Garcia-Rios A, Delgado-Casado N, Gomez-Luna P, Alcala-Diaz JF, et al. Atherosclerosis 2018 Feb;269():50-56
Mediterranean Diet Supplemented With Coenzyme Q(10) Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women
Lopez-Moreno J, Quintana-Navarro GM, Delgado-Lista J, Garcia-Rios A, Alcala-Diaz JF, et al. The journals of gerontology. Series A, Biological sciences and medical sciences 2018 Mar 2;73(3):340-346
Metabotypes of response to bariatric surgery independent of the magnitude of weight loss
Palau-Rodriguez M, Tulipani S, Marco-Ramell A, Miñarro A, Jáuregui O, et al. PloS one 2018;13(6):e0198214
New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility
Lambertos A, Ramos-Molina B, López-Contreras AJ, Cremades A, Peñafiel R PloS one 2018;13(12):e0209202
Pharmacokinetic drug evaluation of exenatide for the treatment of type 2 diabetes
Molina Vega M, Muñoz-Garach A, Tinahones FJ Expert opinion on drug metabolism & toxicology 2018 Feb;14(2):207-217
Quantitative evaluation of capillaroscopic microvascular changes in patients with established coronary heart disease
Sanchez-Garcia ME, Ramirez-Lara I, Gomez-Delgado F, Yubero-Serrano EM, Leon-Acuña A, et al. Medicina clinica 2018 Feb 23;150(4):131-137
Radiotherapy in soft-tissue sarcoma of the extremities
Correa R, Gómez-Millán J, Lobato M, Fernández A, Ordoñez R, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1127-1135
Role of Oral Nutritional Supplements Enriched with B-hydroxy-B-Methylbutyrate in Maintaining Muscle Function and Improving Clinical Outcomes in Various Clinical Settings
Sanz-Paris A, Camprubi-Robles M, Lopez-Pedrosa JM, Pereira SL, Rueda R, et al. The journal of nutrition, health & aging 2018;22(6):664-675
Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial.
Sánchez-Villegas A, Álvarez-Pérez J, Toledo E, Salas-Salvadó J, Ortega-Azorín C, et al. Nutrients 2018 Dec 18;10(12):
Secondary male hypogonadism: a prevalent but overlooked comorbidity of obesity
Molina-Vega M, Muñoz-Garach A, Damas-Fuentes M, Fernández-García JC, Tinahones FJ Asian journal of andrology 2018 Nov-Dec;20(6):531-538
The caveolae-associated coiled-coil protein, NECC2, regulates insulin signalling in Adipocytes
Trávez A, Rabanal-Ruiz Y, López-Alcalá J, Molero-Murillo L, Díaz-Ruiz A, et al. Journal of cellular and molecular medicine 2018 Nov;22(11):5648-5661
The changes in the transcriptomic profiling of subcutaneous adipose tissue after bariatric surgery depend on the insulin resistance state
González-Plaza JJ, Santiago-Fernández C, Gutiérrez-Repiso C, García-Serrano S, Rodriguez-Pacheco F, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2018 Aug;14(8):1182-1191
The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase
Lambertos A, Ramos-Molina B, Cerezo D, López-Contreras AJ, Peñafiel R Biochimica et biophysica acta. General subjects 2018 Mar;1862(3):365-376
The role of muscle in disease-related malnutrition. Decalogue of Good Practices
Almeida, JMG; Ambros, HB; Terrados, N; Barriuso, RS; Pedrosa, JML; Gorgona, NC; Roman, DDL PROGRESS IN NUTRITION 2018
The role of stereotactic body radiotherapy in reirradiation of head and neck cancer recurrence
Román A A, Jodar C, Perez-Rozos A, Lupiañez-Perez Y, Medina JA, et al. Critical reviews in oncology/hematology 2018 Feb;122():194-201
The safety of DPP-4 inhibitor and SGLT2 inhibitor combination therapies
Molina-Vega M, Muñoz-Garach A, Fernández-García JC, Tinahones FJ Expert opinion on drug safety 2018 Aug;17(8):815-824
The Urinary Tract Microbiome in Health and Disease.
Aragón IM, Herrera-Imbroda B, Queipo-Ortuño MI, Castillo E, Del Moral JS, et al. European urology focus 2018 Jan;4(1):128-138
Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery
López S, García-Serrano S, Gutierrez-Repiso C, Rodríguez-Pacheco F, Ho-Plagaro A, et al. Obesity surgery 2018 Sep;28(9):2774-2782
Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the PREDIMED-plus study
Mallorquí-Bagué N, Lozano-Madrid M, Toledo E, Corella D, Salas-Salvadó J, et al. Scientific reports 2018 Oct 31;8(1):16128
Tyrosine kinase inhibitors in iodine-refractory differentiated thyroid cancer: experience in clinical practice
Molina-Vega M, García-Alemán J, Sebastián-Ochoa A, Mancha-Doblas I, Trigo-Pérez JM, et al. Endocrine 2018 Feb;59(2):395-401
Untargeted Profiling of Concordant/Discordant Phenotypes of High Insulin Resistance and Obesity To Predict the Risk of Developing Diabetes
Marco-Ramell A, Tulipani S, Palau-Rodriguez M, Gonzalez-Dominguez R, Miñarro A, et al. Journal of proteome research 2018 Jul 6;17(7):2307-2317
Adherence and tolerance as key in brake on weight loss in cancer patients with nutritional risk after intervention with a high calorie nutritional and specific hyperproteic supplement
García Almeida JM, Lupiáñez Pérez Y, Blanco Naveira M, Ruiz Nava J, Medina JA, et al. Nutricion hospitalaria 2017 Jun 5;34(3):524-531
Adipogenic Impairment of Adipose Tissue-Derived Mesenchymal Stem Cells in Subjects With Metabolic Syndrome: Possible Protective Role of FGF2
Oliva-Olivera W, Coín-Aragüez L, Lhamyani S, Clemente-Postigo M, Torres JA, et al. The Journal of clinical endocrinology and metabolism 2017 Feb 1;102(2):478-487
Adipose tissue biomarkers involved in early resolution of type 2 diabetes after bariatric surgery
Garrido-Sánchez L, Tomé M, Santiago-Fernández C, García-Serrano S, García-Fuentes E, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2017 Jan;13(1):70-77
An increase in visceral fat is associated with a decrease in the taste and olfactory capacity
Fernandez-Garcia JC, Alcaide J, Santiago-Fernandez C, Roca-Rodriguez MM, Aguera Z, et al. PloS one 2017;12(2):e0171204
BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas
Ibáñez-Costa A, López-Sánchez LM, Gahete MD, Rivero-Cortés E, Vázquez-Borrego MC, et al. Scientific reports 2017 Feb 9;7():42002
Brain Functional Connectivity Is Modified by a Hypocaloric Mediterranean Diet and Physical Activity in Obese Women
García-Casares N, Bernal-López MR, Roé-Vellvé N, Gutiérrez-Bedmar M, Fernández-García JC, et al. Nutrients 2017 Jul 1;9(7):
Cardioprotective efficacy of sevoflurane vs. propofol during induction and/or maintenance in patients undergoing coronary artery revascularization surgery without pump: A randomized trial
Guerrero Orriach JL, Galán Ortega M, Ramirez Fernandez A, Ramirez Aliaga M, Moreno Cortes MI, et al. International journal of cardiology 2017 Sep 15;243():73-80
CD36 overexpression: a possible etiopathogenic mechanism of atherosclerosis in patients with prediabetes and diabetes
Lopez-Carmona MD, Plaza-Seron MC, Vargas-Candela A, Tinahones FJ, Gomez-Huelgas R, et al. Diabetology & metabolic syndrome 2017;9():55
Changes in SCD gene DNA methylation after bariatric surgery in morbidly obese patients are associated with free fatty acids
Morcillo S, Martín-Núñez GM, García-Serrano S, Gutierrez-Repiso C, Rodriguez-Pacheco F, et al. Scientific reports 2017 Apr 10;7():46292
Characterization of lipid profile by nuclear magnetic resonance spectroscopy (H-1 NMR) of metabolically healthy obese women after weight loss with Mediterranean diet and physical exercise
Rodriguez-Garcia E, Ruiz-Nava J, Santamaria-Fernandez S, Fernandez-Garcia JC, Vargas-Candela A, et al. Medicine 2017 Jul;96(27):e7040
Consensus statement for use and technical requirements of thyroid ultrasound in endocrinology units
Martín-Hernández T, Díez Gómez JJ, Díaz-Soto G, Torres Cuadro A, Navarro González E, et al. Endocrinologia, diabetes y nutricion 2017 Mar;64 Suppl 1():23-30
Design and rationale of the ODYSSEY DM-DYSLIPIDEMIA trial: lipid-lowering efficacy and safety of alirocumab in individuals with type 2 diabetes and mixed dyslipidaemia at high cardiovascular risk
Müller-Wieland D, Leiter LA, Cariou B, Letierce A, Colhoun HM, et al. Cardiovascular diabetology 2017 May 25;16(1):70
Dietary fat may modulate adipose tissue homeostasis through the processes of autophagy and apoptosis
Camargo A, Rangel-Zúñiga OA, Alcalá-Díaz J, Gomez-Delgado F, Delgado-Lista J, et al. European journal of nutrition 2017 Jun;56(4):1621-1628
Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome
Lopez-Moreno J, Quintana-Navarro GM, Camargo A, Jimenez-Lucena R, Delgado-Lista J, et al. Molecular nutrition & food research 2017 Aug;61(8):
Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
Oliva-Olivera W, Moreno-Indias I, Coín-Aragüez L, Lhamyani S, Alcaide Torres J, et al. PloS one 2017;12(11):e0188324
Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response
López-Moreno J, García-Carpintero S, Jimenez-Lucena R, Haro C, Rangel-Zúñiga OA, et al. Journal of agricultural and food chemistry 2017 Sep 6;65(35):7756-7763
Efficacy and safety of alirocumab in insulin-treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The ODYSSEY DM-INSULIN randomized trial
Leiter LA, Cariou B, Müller-Wieland D, Colhoun HM, Del Prato S, et al. Diabetes, obesity & metabolism 2017 Dec;19(12):1781-1792
Efficacy and safety of alirocumab in insulin-treated patients with type 1 or type 2 diabetes and high cardiovascular risk: Rationale and design of the ODYSSEY DM-INSULIN trial
Cariou B, Leiter LA, Müller-Wieland D, Bigot G, Colhoun HM, et al. Diabetes & metabolism 2017 Oct;43(5):453-459
Evaluation of a New Digital Automated Glycemic Pattern Detection Tool
Comellas MJ, Albiñana E, Artes M, Corcoy R, Fernández-García D, et al. Diabetes technology & therapeutics 2017 Nov;19(11):633-640
Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure
Pérez-Belmonte LM, Moreno-Santos I, Gómez-Doblas JJ, García-Pinilla JM, Morcillo-Hidalgo L, et al. International journal of medical sciences 2017;14(9):891-895
Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study
Pérez-Belmonte LM, Moreno-Santos I, Cabrera-Bueno F, Sánchez-Espín G, Castellano D, et al. International journal of medical sciences 2017;14(3):268-274
Fgf21 is required for cardiac remodeling in pregnancy
Redondo-Angulo I, Mas-Stachurska A, Sitges M, Tinahones FJ, Giralt M, et al. Cardiovascular research 2017 Nov 1;113(13):1574-1584
Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population
Winters A, Ramos-Molina B, Jarvela TS, Yerges-Armstrong L, Pollin TI, et al. Diabetes research and clinical practice 2017 Sep;131():82-90
Ghrelin levels could be involved in the improvement of insulin resistance after bariatric surgery
Santiago-Fernández C, García-Serrano S, Tome M, Valdes S, Ocaña-Wilhelmi L, et al. Endocrinologia, diabetes y nutricion 2017 Aug – Sep;64(7):355-362
Growth hormone-releasing hormone is produced by adipocytes and regulates lipolysis through growth hormone receptor
Rodríguez-Pacheco F, Gutierrez-Repiso C, García-Serrano S, Ho-Plagaro A, Gómez-Zumaquero JM, et al. International journal of obesity (2005) 2017 Oct;41(10):1547-1555
How Can a Good Idea Fail? Basal Insulin Peglispro [LY2605541] for the Treatment of Type 2 Diabetes
Muñoz-Garach A, Molina-Vega M, Tinahones FJ Diabetes therapy : research, treatment and education of diabetes and related disorders 2017 Feb;8(1):9-22
IGFBP-3 Interacts with the Vitamin D Receptor in Insulin Signaling Associated with Obesity in Visceral Adipose Tissue
Moreno-Santos I, Castellano-Castillo D, Lara MF, Fernandez-Garcia JC, Tinahones FJ, et al. International journal of molecular sciences 2017 Nov 7;18(11):
Improving efficacy and efficiency through the implementation of a new organisational model in a Radiation Oncology Department
Lupiañez-Perez Y, Gomez-Millan J, Lobato M, Pedrosa P, Lupiañez-Perez I, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2017 Nov;19(11):1375-1381
Iodine is associated to semen quality in men who undergo consultations for infertility
Partal-Lorente AB, Maldonado-Ezequiel V, Martinez-Navarro L, Herrera-Contreras I, Gutierrez-Repiso C, et al. Reproductive toxicology (Elmsford, N.Y.) 2017 Oct;73():1-7
Jejunal gluconeogenesis associated with insulin resistance level and its evolution after Roux-en-Y gastric bypass
Gutierrez-Repiso C, Garcia-Serrano S, Moreno-Ruiz FJ, Alcain-Martinez G, Rodriguez-Pacheco F, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2017 Apr;13(4):623-630
Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis
Rosique-Esteban N, Díaz-López A, Martínez-González MA, Corella D, Goday A, et al. PloS one 2017;12(3):e0172253
Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation
Pérez-Martínez P, Mikhailidis DP, Athyros VG, Bullo M, Couture P, et al. Nutrition reviews 2017 May 1;75(5):307-326
Linagliptin as add-on to empagliflozin and metformin in patients with type 2 diabetes: Two 24-week randomized, double-blind, double-dummy, parallel-group trials
Tinahones FJ, Gallwitz B, Nordaby M, Götz S, Maldonado-Lutomirsky M, et al. Diabetes, obesity & metabolism 2017 Feb;19(2):266-274
Lixisenatide in patients with type 2 diabetes and obesity: Beyond glycaemic control
Roca-Rodríguez MM, Muros de Fuentes MT, Piédrola-Maroto G, Quesada-Charneco M, Maraver-Selfa S, et al. Atencion primaria 2017 May;49(5):294-299
Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids
Monastero R, García-Serrano S, Lago-Sampedro A, Rodríguez-Pacheco F, Colomo N, et al. European journal of nutrition 2017 Mar;56(2):715-726
Molecular effect of fenofibrate on PBMC gene transcription related to lipid metabolism in patients with metabolic syndrome
Moreno-Indias I, Tinahones FJ, Clemente-Postigo M, Castellano-Castillo D, Fernández-García JC, et al. Clinical endocrinology 2017 Jun;86(6):784-790
Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic syndrome
Oliva-Olivera W, Lhamyani S, Coín-Aragüez L, Castellano-Castillo D, Alcaide-Torres J, et al. Metabolism: clinical and experimental 2017 Jun;71():132-143
Nitrogenous content in parenteral nutrition: a four-year experience in a general hospital. Critically-ill patient specificity
Villalobos-Gámez JL, Lara-Ramos C, Domínguez-Rivas Y, Vallejo-Báez A, Cota-Delgado F, et al. Nutricion hospitalaria 2017 Jun 5;34(3):555-561
No effect of different bariatric surgery procedures on LINE-1 DNA methylation in diabetic and nondiabetic morbidly obese patients
Martín-Núñez GM, Cabrera-Mulero A, Alcaide-Torres J, García-Fuentes E, Tinahones FJ, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2017 Mar;13(3):442-450
Obesity and menopause modify the epigenomic profile of breast cancer
Crujeiras AB, Diaz-Lagares A, Stefansson OA, Macias-Gonzalez M, Sandoval J, et al. Endocrine-related cancer 2017 Jul;24(7):351-363
Peculiarities of the obese patient with cancer: a national consensus statement by the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
Pérez-Segura P, Palacio JE, Vázquez L, Monereo S, de Las Peñas R, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2017 Jun;19(6):682-694
Plasma FGF21 levels in obese patients undergoing energy-restricted diets or bariatric surgery: a marker of metabolic stress?
Crujeiras AB, Gomez-Arbelaez D, Zulet MA, Carreira MC, Sajoux I, et al. International journal of obesity (2005) 2017 Oct;41(10):1570-1578
Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study
Valdés S, Maldonado-Araque C, Lago-Sampedro A, Lillo JA, Garcia-Fuentes E, et al. Thyroid : official journal of the American Thyroid Association 2017 Feb;27(2):156-166
Reference Values for TSH may be Inadequate to Define Hypothyroidism in Persons with Morbid Obesity: Di@bet.es Study
Valdés S, Maldonado-Araque C, Lago-Sampedro A, Lillo-Muñoz JA, Garcia-Fuentes E, et al. Obesity (Silver Spring, Md.) 2017 Apr;25(4):788-793
Role of Gut Microbiota on Cardio-Metabolic Parameters and Immunity in Coronary Artery Disease Patients with and without Type-2 Diabetes Mellitus
Sanchez-Alcoholado L, Castellano-Castillo D, Jordán-Martínez L, Moreno-Indias I, Cardila-Cruz P, et al. Frontiers in microbiology 2017;8():1936
Serum metabolites in non-alcoholic fatty-liver disease development or reversion; a targeted metabolomic approach within the PREDIMED trial
Papandreou C, Bullò M, Tinahones FJ, Martínez-González MÁ, Corella D, et al. Nutrition & metabolism 2017;14():58
Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
Mateo F, Arenas EJ, Aguilar H, Serra-Musach J, de Garibay GR, et al. Oncogene 2017 May 11;36(19):2737-2749
Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis
Ejarque M, Ceperuelo-Mallafré V, Serena C, Pachón G, Núñez-Álvarez Y, et al. Cell death & disease 2017 May 18;8(5):e2802
The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice
Romero-Zerbo SY, Ruz-Maldonado I, Espinosa-Jiménez V, Rafacho A, Gómez-Conde AI, et al. Scientific reports 2017 Jun 21;7(1):3946
The Effect of Metabolic and Bariatric Surgery on DNA Methylation Patterns.
Morcillo S, Macías-González M, Tinahones FJ Current atherosclerosis reports 2017 Aug 30;19(10):40
The Impact of Body Mass Index and Nuclear beta-Catenin on Survival in Locally Advanced Rectal Cancer Treated With Preoperative Radiochemotherapy
Gomez-Millan J, Queipo MI, Del Mar Delgado M, Perez-Villa L, Roman A, et al. Journal of surgical oncology 2017 Mar;115(3):301-306
The pro-/anti-inflammatory effects of different fatty acids on visceral adipocytes are partially mediated by GPR120
Rodriguez-Pacheco F, Gutierrez-Repiso C, Garcia-Serrano S, Alaminos-Castillo MA, Ho-Plagaro A, et al. European journal of nutrition 2017 Jun;56(4):1743-1752
The role of vitamin D and VDR in carcinogenesis: Through epidemiology and basic sciences
Bandera Merchan B, Morcillo S, Martin-Nuñez G, Tinahones FJ, Macías-González M The Journal of steroid biochemistry and molecular biology 2017 Mar;167():203-218
Unfavorable cytokine and adhesion molecule profiles during and after pregnancy, in women with gestational diabetes mellitus
Roca-Rodríguez MDM, López-Tinoco C, Fernández-Deudero Á, Murri M, García-Palacios MV, et al. Endocrinologia, diabetes y nutricion 2017 Jan;64(1):18-25
A dysregulation of glucose metabolism control is associated with carotid atherosclerosis in patients with coronary heart disease (CORDIOPREV-DIAB study)
Yubero-Serrano EM, Delgado-Lista J, Alcala-Diaz JF, Garcia-Rios A, Perez-Caballero AI, et al. Atherosclerosis 2016 Oct;253():178-185
A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women
Pastor A, Fernández-Aranda F, Fitó M, Jiménez-Murcia S, Botella C, et al. PloS one 2016;11(2):e0148734
A randomized clinical trial of basal insulin peglispro vs NPH in insulin-naive patients with type 2 diabetes: the IMAGINE 6 trial
Grunberger G, Chen L, Rodriguez A, Tinahones FJ, Jacober SJ, et al. Diabetes, obesity & metabolism 2016 Oct;18 Suppl 2():34-42
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans
Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, et al. Molecular metabolism 2016 Jan;5(1):5-18
Adipose tissue infiltration in normal-weight subjects and its impact on metabolic function
Moreno-Indias I, Oliva-Olivera W, Omiste A, Castellano-Castillo D, Lhamyani S, et al. Translational research : the journal of laboratory and clinical medicine 2016 Jun;172():6-17.e3
An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability
Lima-Cabello E, Garcia-Guirado F, Calvo-Medina R, el Bekay R, Perez-Costillas L, et al. Oxidative medicine and cellular longevity 2016;2016():8548910
An Arab registry for type 1 diabetes: global benefits for type 1 diabetes patients
Zayed H, Ouhtit A, El Bekay R Current medical research and opinion 2016 Oct;32(10):1681-1684
Analysis of elderly patients with diabetes participating in VIDA study on admission
Gomez-Candela, C; Fernandez, LP; Paris, AS; Pelaez, RB; Martin, PM; Almeida, JMG; Palmero, AM NUTRICION HOSPITALARIA 2016
Application of the new ESPEN definition of malnutrition in geriatric diabetic patients during hospitalization: A multicentric study
Sanz-París A, Gómez-Candela C, Martín-Palmero Á, García-Almeida JM, Burgos-Pelaez R, et al. Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1564-1567
Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients
Perez-Martinez P, Alcala-Diaz JF, Kabagambe EK, Garcia-Rios A, Tsai MY, et al. Journal of clinical lipidology 2016 Sep-Oct;10(5):1163-71
Bioavailability of tomato polyphenols is enhanced by processing and fat addition: Evidence from a randomized feeding trial
Martínez-Huélamo M, Vallverdú-Queralt A, Di Lecce G, Valderas-Martínez P, Tulipani S, et al. Molecular nutrition & food research 2016 Jul;60(7):1578-89
Biomarkers of Morbid Obesity and Prediabetes by Metabolomic Profiling of Human Discordant Phenotypes
Tulipani S, Palau-Rodriguez M, Miñarro Alonso A, Cardona F, Marco-Ramell A, et al. Clinica chimica acta; international journal of clinical chemistry 2016 Dec 1;463():53-61
Cardiac, renal, and neurological benefits of preoperative levosimendan administration in patients with right ventricular dysfunction and pulmonary hypertension undergoing cardiac surgery: evaluation with two biomarkers neutrophil gelatinase-associated lipocalin and neuronal enolase
Guerrero-Orriach JL, Ariza-Villanueva D, Florez-Vela A, Garrido-Sánchez L, Moreno-Cortés MI, et al. Therapeutics and clinical risk management 2016;12():623-30
CDK4 is an essential insulin effector in adipocytes
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, et al. The Journal of clinical investigation 2016 Jan;126(1):335-48
Clinical phenotype clustering in cardiovascular risk patients for the identification of responsive metabotypes after red wine polyphenol intake
Vázquez-Fresno R, Llorach R, Perera A, Mandal R, Feliz M, et al. The Journal of nutritional biochemistry 2016 Feb;28():114-20
Commonalities in the Association between PPARG and Vitamin D Related with Obesity and Carcinogenesis
Bandera Merchan B, Tinahones FJ, Macías-González M PPAR research 2016;2016():2308249
Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders?
Mallorquí-Bagué N, Fagundo AB, Jimenez-Murcia S, de la Torre R, Baños RM, et al. PloS one 2016;11(9):e0163901
Diagnosis and treatment of iron deficiency, with or without anemia, before and after bariatric surgery
Jericó C, Bretón I, García Ruiz de Gordejuela A, de Oliveira AC, Rubio MÁ, et al. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 2016 Jan;63(1):32-42
Dietary Epicatechin Is Available to Breastfed Infants through Human Breast Milk in the Form of Host and Microbial Metabolites
Khymenets O, Rabassa M, Rodríguez-Palmero M, Rivero-Urgell M, Urpi-Sarda M, et al. Journal of agricultural and food chemistry 2016 Jul 6;64(26):5354-60
Does Metabolically Healthy Obesity Exist?
Muñoz-Garach A, Cornejo-Pareja I, Tinahones FJ Nutrients 2016 Jun 1;8(6):
Effect of Roux-en-Y gastric bypass-induced weight loss on the transcriptomic profiling of subcutaneous adipose tissue
González-Plaza JJ, Gutiérrez-Repiso C, García-Serrano S, Rodriguez-Pacheco F, Garrido-Sánchez L, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2016 Feb;12(2):257-63
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes
El Bekay R, Coín-Aragüez L, Fernández-García D, Oliva-Olivera W, Bernal-López R, et al. British journal of pharmacology 2016 Jun;173(11):1820-34
Efficacy and safety of a premixed versus a basal-plus insulin regimen as intensification for type 2 diabetes by timing of the main meal
Gross JL, Rojas A, Shah S, Tinahones FJ, Cleall S, et al. Current medical research and opinion 2016 Jun;32(6):1109-16
Efficacy and safety of switching from sitagliptin to liraglutide in subjects with type 2 diabetes (LIRA-SWITCH): a randomized, double-blind, double-dummy, active-controlled 26-week trial
Bailey TS, Takács R, Tinahones FJ, Rao PV, Tsoukas GM, et al. Diabetes, obesity & metabolism 2016 Dec;18(12):1191-1198
Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa
Steward T, Mestre-Bach G, Agüera Z, Granero R, Martín-Romera V, et al. European eating disorders review : the journal of the Eating Disorders Association 2016 Nov;24(6):523-527
Expert Study: Utility of an Automated Bolus Advisor System in Patients with Type 1 Diabetes Treated with Multiple Daily Injections of InsulinA Crossover Study
Gonzalez C, Picón MJ, Tomé M, Pujol I, Fernández-García JC, et al. Diabetes technology & therapeutics 2016 May;18(5):282-7
Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World
Doss CG, Alasmar DR, Bux RI, Sneha P, Bakhsh FD, et al. Scientific reports 2016 Nov 17;6():37284
Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits
Ortega FJ, Agüera Z, Sabater M, Moreno-Navarrete JM, Alonso-Ledesma I, et al. Molecular nutrition & food research 2016 Jul;60(7):1673-83
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
Walford GA, Gustafsson S, Rybin D, Stancáková A, Chen H, et al. Diabetes 2016 Oct;65(10):3200-11
Glycemic control and maternal and fetal outcomes in pregnant women with type 1 diabetes according to the type of basal insulin
Chico A, Herranz L, Corcoy R, Ramírez O, Goya MM, et al. European journal of obstetrics, gynecology, and reproductive biology 2016 Nov;206():84-91
Gut microbiota and type 2 diabetes mellitus
Muñoz-Garach A, Diaz-Perdigones C, Tinahones FJ Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 2016 Dec;63(10):560-568
Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
Talavera-Garcia E, Delgado-Lista J, Garcia-Rios A, Delgado-Casado N, Gomez-Luna P, et al. PloS one 2016;11(4):e0153096
Insulin resistance is associated with specific gut microbiota in appendix samples from morbidly obese patients
Moreno-Indias I, Sánchez-Alcoholado L, García-Fuentes E, Cardona F, Queipo-Ortuño MI, et al. American journal of translational research 2016;8(12):5672-5684
Interaction Between Orexin-A and Sleep Quality in Females in Extreme Weight Conditions
Sauchelli S, Jiménez-Murcia S, Fernández-García JC, Garrido-Sánchez L, Tinahones FJ, et al. European eating disorders review : the journal of the Eating Disorders Association 2016 Nov;24(6):510-517
Metabolomics-Guided Insights on Bariatric Surgery Versus Behavioral Interventions for Weight Loss
Tulipani S, Griffin J, Palau-Rodriguez M, Mora-Cubillos X, Bernal-Lopez RM, et al. Obesity (Silver Spring, Md.) 2016 Dec;24(12):2451-2466
Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity
Fagundo AB, Jiménez-Murcia S, Giner-Bartolomé C, Agüera Z, Sauchelli S, et al. Scientific reports 2016 Aug 1;6():30820
Neonatal androgen exposure causes persistent gut microbiota dysbiosis related to metabolic disease in adult female rats.
Moreno-Indias I, Sánchez-Alcoholado L, Sánchez-Garrido MÁ, Martín-Núñez GM, Pérez-Jiménez F, et al. Endocrinology 2016 Dec;157(12):4888-4898
Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice
Moreno-Indias I, Torres M, Sanchez-Alcoholado L, Cardona F, Almendros I, et al. Sleep 2016 Oct 1;39(10):1891-1897
Obesity Determines the Immunophenotypic Profile and Functional Characteristics of Human Mesenchymal Stem Cells From Adipose Tissue
Pachón-Peña G, Serena C, Ejarque M, Petriz J, Duran X, et al. Stem cells translational medicine 2016 Apr;5(4):464-75
Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome
Sauchelli S, Jiménez-Murcia S, Sánchez I, Riesco N, Custal N, et al. Psychoneuroendocrinology 2016 Mar;65():102-8
PDE5A Polymorphisms Influence on Sildenafil Treatment Success
Marchal-Escalona C, Herrera-Imbroda B, Clemente-Postigo M, Alcaide-Torres J, Quiñonero A, et al. The journal of sexual medicine 2016 Jul;13(7):1104-10
Prandial Options to Advance Basal Insulin Glargine Therapy: Testing Lixisenatide Plus Basal Insulin Versus Insulin Glulisine Either as Basal-Plus or Basal-Bolus in Type 2 Diabetes: The GetGoal Duo-2 Trial
Rosenstock J, Guerci B, Hanefeld M, Gentile S, Aronson R, et al. Diabetes care 2016 Aug;39(8):1318-28
Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients
Moreno-Indias I, Sánchez-Alcoholado L, Pérez-Martínez P, Andrés-Lacueva C, Cardona F, et al. Food & function 2016 Apr;7(4):1775-87
RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
Gentile AM, Lhamyani S, Coín-Aragüez L, Oliva-Olivera W, Zayed H, et al. PloS one 2016;11(6):e0157002
Smell-taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions
Fernández-Aranda F, Agüera Z, Fernández-García JC, Garrido-Sanchez L, Alcaide-Torres J, et al. Endocrine 2016 Feb;51(2):256-67
The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
Bermudez-Silva FJ, Romero-Zerbo SY, Haissaguerre M, Ruz-Maldonado I, Lhamyani S, et al. Disease models & mechanisms 2016 Jan;9(1):51-61
TNFA gene variants related to the inflammatory status and its association with cellular aging: From the CORDIOPREV study
Rangel-Zúñiga OA, Corina A, Lucena-Porras B, Cruz-Teno C, Gómez-Delgado F, et al. Experimental gerontology 2016 Oct;83():56-62
Trends in Bariatric Surgery in Spain in the Twenty-First Century: Baseline Results and 1-Month Follow Up of the RICIBA, a National Registry
Lecube A, de Hollanda A, Calañas A, Vilarrasa N, Rubio MA, et al. Obesity surgery 2016 Aug;26(8):1836-42
Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population
Haro C, Montes-Borrego M, Rangel-Zúñiga OA, Alcalá-Díaz JF, Gómez-Delgado F, et al. The Journal of clinical endocrinology and metabolism 2016 Jan;101(1):233-42
Type 2 diabetes is associated with decreased PGC1 alpha expression in epicardial adipose tissue of patients with coronary artery disease
Moreno-Santos I, Pérez-Belmonte LM, Macías-González M, Mataró MJ, Castellano D, et al. Journal of translational medicine 2016 Aug 19;14(1):243
Virgin olive oil rich in phenolic compounds modulates the expression of atherosclerosis-related genes in vascular endothelium
Meza-Miranda ER, Rangel-Zúñiga OA, Marín C, Pérez-Martínez P, Delgado-Lista J, et al. European journal of nutrition 2016 Mar;55(2):519-527
Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.
Yew Tan C, Virtue S, Murfitt S, Roberts LD, Phua YH, et al. Scientific reports 2015 Dec 17;5():18366
Advances in the treatment of prostate cancer with radiotherapy
Gómez-Millán J, Lara MF, Correa Generoso R, Perez-Rozos A, Lupiáñez-Pérez Y, et al. Critical reviews in oncology/hematology 2015 Aug;95(2):144-53
Changes in Body Composition in Anorexia Nervosa: Predictors of Recovery and Treatment Outcome
Agüera Z, Romero X, Arcelus J, Sánchez I, Riesco N, et al. PloS one 2015;10(11):e0143012
Changes in thyroid function with age: results from the Pizarra population-based longitudinal study
Lago-Sampedro AM, Gutiérrez-Repiso C, Valdés S, Maldonado C, Colomo N, et al. International journal of clinical practice 2015 May;69(5):577-87
Cilostazol Does not Improve Peripheral Arterial Disease-Linked Oxidative Stress
Bernal-Lopez MR, Peña D, Gomez-Martin P, Tinahones FJ, Gomez-Huelgas R Cardiovascular therapeutics 2015 Feb;33(1):15-9
Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women
Barja-Fernández S, Folgueira C, Seoane LM, Casanueva FF, Dieguez C, et al. The Journal of clinical endocrinology and metabolism 2015 Sep;100(9):E1188-96
Differences in the Osteogenic Differentiation Capacity of Omental Adipose-Derived Stem Cells in Obese Patients With and Without Metabolic Syndrome.
Oliva-Olivera W, Leiva Gea A, Lhamyani S, Coín-Aragüez L, Alcaide Torres J, et al. Endocrinology 2015 Dec;156(12):4492-501
Effects of a long-term lifestyle intervention program with Mediterranean diet and exercise for the management of patients with metabolic syndrome in a primary care setting
Gomez-Huelgas R, Jansen-Chaparro S, Baca-Osorio AJ, Mancera-Romero J, Tinahones FJ, et al. European journal of internal medicine 2015 Jun;26(5):317-23
Effects of exercise on inflammation in cardiac rehabilitation
Roca-Rodríguez Mdel M, Garrido-Sánchez L, García-Almeida JM, Ruiz-Nava J, Alcaide-Torres J, et al. Nutricion hospitalaria 2015 Jun 1;31(6):2633-40
Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue
García-Fuentes E, Santiago-Fernández C, Gutiérrez-Repiso C, Mayas MD, Oliva-Olivera W, et al. Journal of translational medicine 2015 Nov 30;13():373
Impaired Adipose Tissue Expandability and Lipogenic Capacities as Ones of the Main Causes of Metabolic Disorders
Moreno-Indias I, Tinahones FJ Journal of diabetes research 2015;2015():970375
Incidence and care-related costs of severe hypoglycaemia requiring emergency treatment in Andalusia (Spain): the PAUEPAD project
Barranco RJ, Gomez-Peralta F, Abreu C, Delgado M, Palomares R, et al. Diabetic medicine : a journal of the British Diabetic Association 2015 Nov;32(11):1520-6
Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of degs1 Impairs Adipocyte Differentiation and Function
Barbarroja N, Rodriguez-Cuenca S, Nygren H, Camargo A, Pirraco A, et al. Diabetes 2015 Apr;64(4):1180-92
Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study
Yubero-Serrano EM, Delgado-Lista J, Tierney AC, Perez-Martinez P, Garcia-Rios A, et al. The American journal of clinical nutrition 2015 Dec;102(6):1509-17
Intermittent hypoxia alters gut microbiota diversity in a mouse model of sleep apnoea
Moreno-Indias I, Torres M, Montserrat JM, Sanchez-Alcoholado L, Cardona F, et al. The European respiratory journal 2015 Apr;45(4):1055-65
Lipopolysaccharide and lipopolysaccharide-binding protein levels and their relationship to early metabolic improvement after bariatric surgery
Clemente-Postigo M, Roca-Rodriguez Mdel M, Camargo A, Ocaña-Wilhelmi L, Cardona F, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2015 Jul-Aug;11(4):933-9
Long-term effects of varying consumption of omega 3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy
Roca-Rodríguez Mdel M, García-Almeida JM, Ruiz-Nava J, Alcaide J, Lupiañez-Pérez Y, et al. International journal of food sciences and nutrition 2015 Feb;66(1):108-13
Metabolomic insights into the intricate gut microbial-host interaction in the development of obesity and type 2 diabetes
Palau-Rodriguez M, Tulipani S, Isabel Queipo-Ortuño M, Urpi-Sarda M, Tinahones FJ, et al. Frontiers in microbiology 2015;6():1151
Modulation of Higher-Order Olfaction Components on Executive Functions in Humans
Fagundo AB, Jiménez-Murcia S, Giner-Bartolomé C, Islam MA, de la Torre R, et al. PloS one 2015;10(6):e0130319
Myocardial Ischemic Subject’s Thymus Fat: A Novel Source of Multipotent Stromal Cells.
Oliva-Olivera W, Coín-Aragüez L, Salas J, Lhamyani S, Gentile AM, et al. PloS one 2015;10(12):e0144401
New and Vintage Solutions To Enhance the Plasma Metabolome Coverage by LC-ESI-MS Untargeted Metabolomics: The Not-So-Simple Process of Method Performance Evaluation
Tulipani S, Mora-Cubillos X, Jáuregui O, Llorach R, García-Fuentes E, et al. Analytical chemistry 2015 Mar 3;87(5):2639-47
Newly impaired glucose metabolism and prognosis after percutaneous revascularization
Jiménez-Navarro MF, Fernández-Pastor J, Garrido-Sánchez L, Molina-Mora MJ, Ortiz-García C, et al. Cardiology journal 2015;22(1):44-51
Novel Oxazolidinone-Based Peroxisome Proliferator Activated Receptor Agonists: Molecular Modeling, Synthesis, and Biological Evaluation
Fresno N, Macías-González M, Torres-Zaguirre A, Romero-Cuevas M, Sanz-Camacho P, et al. Journal of medicinal chemistry 2015 Aug 27;58(16):6639-52
Nutrimetabolomics fingerprinting to identify biomarkers of bread exposure in a free-living population from the PREDIMED study cohort
Garcia-Aloy, M; Llorach, R; Urpi-Sarda, M; Tulipani, S; Salas-Salvado, J; Martinez-Gonzalez, MA; Corella, D; Fito, M; Estruch, R; Serra-Majem, L; Andres-Lacueva, C METABOLOMICS 2015
Obesity as a risk factor in cancer: A national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
Goday A, Barneto I, García-Almeida JM, Blasco A, Lecube A, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2015 Oct;17(10):763-71
Olfaction in eating disorders and abnormal eating behavior: a systematic review
Islam MA, Fagundo AB, Arcelus J, Agüera Z, Jiménez-Murcia S, et al. Frontiers in psychology 2015;6():1431
Parathyroid Hormone-Related Protein, Human Adipose-Derived Stem Cells Adipogenic Capacity and Healthy Obesity
Roca-Rodríguez MM, El Bekay R, Garrido-Sanchez L, Gómez-Serrano M, Coin-Aragüez L, et al. The Journal of clinical endocrinology and metabolism 2015 Jun;100(6):E826-35
PHARMACONUTRITION IN SEVERELY ILL PATIENT
Burgos Peláez R, Escudero Álvarez E, García Almeida JM, García de Lorenzo A, García Luna PP, et al. Nutricion hospitalaria 2015 Aug 1;32(2):478-86
Phenolic and microbial-targeted metabolomics to discovering and evaluating wine intake biomarkers in human urine and plasma
Urpi-Sarda M, Boto-Ordóñez M, Queipo-Ortuño MI, Tulipani S, Corella D, et al. Electrophoresis 2015 Sep;36(18):2259-2268
Physical activity in anorexia nervosa: How relevant is it to therapy response?
Sauchelli S, Arcelus J, Sánchez I, Riesco N, Jiménez-Murcia S, et al. European psychiatry : the journal of the Association of European Psychiatrists 2015 Nov;30(8):924-31
Polymorphisms in Endothelin System Genes, Arsenic Levels and Obesity Risk
Martínez-Barquero V, de Marco G, Martínez-Hervas S, Rentero P, Galan-Chilet I, et al. PloS one 2015;10(3):e0118471
Potential advantages of volumetric arc therapy in head and neck cancer
Gomez-Millan Barrachina J, Jerez Sainz I, Perez Rozos A, Ramirez Ros JC, Toledo Serrano MD, et al. Head & neck 2015 Jun;37(6):909-14
Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity
Díaz-Ruiz A, Guzmán-Ruiz R, Moreno NR, García-Rios A, Delgado-Casado N, et al. Antioxidants & redox signaling 2015 Sep 1;23(7):597-612
Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids
Rangel-Zúñiga OA, Camargo A, Marin C, Peña-Orihuela P, Pérez-Martínez P, et al. BMC genomics 2015 Jul 8;16():509
Sensitive and Rapid UHPLC-MS/MS for the Analysis of Tomato Phenolics in Human Biological Samples
Martínez-Huélamo M, Tulipani S, Jáuregui O, Valderas-Martinez P, Vallverdú-Queralt A, et al. Molecules (Basel, Switzerland) 2015 Nov 16;20(11):20409-25
Serum 25-Hydroxyvitamin D and Adipose Tissue Vitamin D Receptor Gene Expression: Relationship With Obesity and Type 2 Diabetes
Clemente-Postigo M, Muñoz-Garach A, Serrano M, Garrido-Sánchez L, Bernal-López MR, et al. The Journal of clinical endocrinology and metabolism 2015 Apr;100(4):E591-5
Surgery-Induced Weight Loss Is Associated With the Downregulation of Genes Targeted by MicroRNAs in Adipose Tissue
Ortega FJ, Mercader JM, Moreno-Navarrete JM, Nonell L, Puigdecanet E, et al. The Journal of clinical endocrinology and metabolism 2015 Nov;100(11):E1467-76
The effect of colostrum source (goat vs. sheep) and timing of the first colostrum feeding (2 h vs. 14 h after birth) on body weight and immune status of artificially reared newborn lambs
Hernández-Castellano LE, Morales-delaNuez A, Sánchez-Macías D, Moreno-Indias I, Torres A, et al. Journal of dairy science 2015 Jan;98(1):204-10
The effect of milk source on body weight and immune status of lambs
Hernandez-Castellano, LE; Moreno-Indias, I; Morales-delaNuez, A; Sanchez-Macias, D; Torres, A; Capote, J; Arguello, A; Castro, N LIVESTOCK SCIENCE 2015
The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance
Gutierrez-Repiso C, Rodriguez-Pacheco F, Garcia-Arnes J, Valdes S, Gonzalo M, et al. Laboratory investigation; a journal of technical methods and pathology 2015 Dec;95(12):1409-17
The frequency and impact of hypoglycemia among hospitalized patients with diabetes: A population-based study.
Gómez-Huelgas R, Guijarro-Merino R, Zapatero A, Barba R, Guijarro-Contreras A, et al. Journal of diabetes and its complications 2015 Nov-Dec;29(8):1050-5
The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study
Mansego ML, De Marco G, Ivorra C, Lopez-Izquierdo R, Morcillo S, et al. Journal of translational medicine 2015 Sep 2;13():286
The tomato sauce making process affects the bioaccessibility and bioavailability of tomato phenolics: A pharmacokinetic study
Martínez-Huélamo M, Tulipani S, Estruch R, Escribano E, Illán M, et al. Food chemistry 2015 Apr 15;173():864-72
Zinc-alpha 2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase
Ceperuelo-Mallafré V, Ejarque M, Duran X, Pachón G, Vázquez-Carballo A, et al. PloS one 2015;10(6):e0129644
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