Laboratorio de Dendrímeros Biomiméticos y Fotónica
Lineas de Investigación
01. Preparación de estructuras dendrimericas para emular macromoléculas bioactivas multivalentes y visualizar sus interacciones.
02. Síntesis de nuevos sistemas dendrímeros y dendrones convenientemente funcionalizados.
03. Preparación de soportes sólidos (nanopartículas) para su funcioanlizació`n con sistemas dendriméricos.
04. PSíntesis de marcadores fluorescentes para sistemas dendriméricos.
05. Diseño y síntesis de sensores para el procesamiento de información biomédica.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
Área 6.IBIMA Tech: Área Tecnología en Salud e Innovación
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludMOV19-001 Síntesis de nuevos cromóforos bifotónicos para aplicaciones en bioimagen.
Instituto de Investigación Biomédica de Málaga (IBIMA)PI-0250-2016 Desarrollo de Nuevos Nanobiosensores para el ..Desarrollo de Nuevos Nanobiosensores para el Diagnostico de Reacciones Adversas A Medicamentos
CONSEJERÍA DE SALUDPatentes y Tecnologías
Nanoestructuras para el diagnóstico de alergias a amoxicilina.
Montañez Vega, María Isabel
Mayorga Mayorga, Cristobalina
Torres Jaen, Maria Jose
Fernandez Duarte, Tahia
Rodriguez Nogales, Alba
Perez-Inestrosa Villatoro, Ezequiel
Vida Pol, Yolanda
Mayorga Mayorga, Cristobalina
Torres Jaen, Maria Jose
Fernandez Duarte, Tahia
Rodriguez Nogales, Alba
Perez-Inestrosa Villatoro, Ezequiel
Vida Pol, Yolanda
Fernandez Duarte, Tahia
Rodriguez Nogales, Alba
Perez-Inestrosa Villatoro, Ezequiel
Vida Pol, Yolanda
Perez-Inestrosa Villatoro, Ezequiel
Vida Pol, Yolanda
Nuevos compuestos para el diagnóstico de alergia a cefalosporinas
Montañez Vega, María Isabel
Mayorga Mayorga, Cristobalina
Martin-Serrano Ortiz, Angela
Doña Díaz, Inmaculada
Torres Jaen, Maria Jose
Perez-Inestrosa Villatoro, Ezequiel
Mayorga Mayorga, Cristobalina
Martin-Serrano Ortiz, Angela
Doña Díaz, Inmaculada
Torres Jaen, Maria Jose
Perez-Inestrosa Villatoro, Ezequiel
Doña Díaz, Inmaculada
Torres Jaen, Maria Jose
Perez-Inestrosa Villatoro, Ezequiel
Perez-Inestrosa Villatoro, Ezequiel
Composición útil en la detección de alergia a ácido clavulánico
Montañez Vega, María Isabel
Mayorga Mayorga, Cristobalina
Torres Jaen, Maria Jose
Fernandez Duarte, Tahia
Ariza Veguillas, Adriana
Perez-Inestrosa Villatoro, Ezequiel
Najera Albendin, Francisco
Vida Pol, Yolanda
Mayorga Mayorga, Cristobalina
Torres Jaen, Maria Jose
Fernandez Duarte, Tahia
Ariza Veguillas, Adriana
Perez-Inestrosa Villatoro, Ezequiel
Najera Albendin, Francisco
Vida Pol, Yolanda
Fernandez Duarte, Tahia
Ariza Veguillas, Adriana
Perez-Inestrosa Villatoro, Ezequiel
Najera Albendin, Francisco
Vida Pol, Yolanda
Perez-Inestrosa Villatoro, Ezequiel
Najera Albendin, Francisco
Vida Pol, Yolanda
Vida Pol, Yolanda
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
ARADyAL: The Spanish Multidisciplinary Research Network for Allergic Diseases
Torres MJ, Agundez J, Barber D, Bartra J, Davila I, et al. Journal of investigational allergology & clinical immunology 2021 Apr 20;31(2):108-119
Dynamic Covalent Properties of a Novel Indolo[3,2-b]carbazole Diradical
Badía-Domínguez I, Peña-Álvarez M, Wang D, Pérez Guardiola A, Vida Y, et al. Chemistry (Weinheim an der Bergstrasse, Germany) 2021 Mar 22;27(17):5509-5520
E/Z Molecular Photoswitches Activated by Two-Photon Absorption: Comparison between Different Families
Marazzi M, García-Iriepa C, Benitez-Martin C, Najera F, Monari A, et al. Molecules (Basel, Switzerland) 2021 Dec 5;26(23):
Emerging glyco-based strategies to steer immune responses
Anderluh M, Berti F, Bzducha-Wróbel A, Chiodo F, Colombo C, et al. The FEBS journal 2021 Aug;288(16):4746-4772
Multiepitope Dendrimeric Antigen-Silica Particle Composites as Nano-Based Platforms for Specific Recognition of IgEs
Gil-Ocaña V, Jimenez IM, Mayorga C, Doña I, Céspedes JA, et al. Frontiers in immunology 2021;12():750109
Rapid amplitude-modulation of a diarylethene photoswitch: en route to contrast-enhanced fluorescence imaging
Naren G, Larsson W, Benitez-Martin C, Li S, Pérez-Inestrosa E, et al. Chemical science 2021 Apr 15;12(20):7073-7078
Role of nanostructures in allergy: Diagnostics, treatments and safety
Mayorga C, Perez-Inestrosa E, Rojo J, Ferrer M, Montañez MI Allergy 2021 Nov;76(11):3292-3306
Semiautomatic method for the ultra-trace arsenic speciation in environmental and biological samples via magnetic solid phase extraction prior to HPLC-ICP-MS determination
Montoro-Leal P, García-Mesa JC, Morales-Benítez I, García de Torres A, Vereda Alonso E Talanta 2021 Dec 1;235():122769
Slightly congested amino terminal dendrimers. The synthesis of amide-based stable structures on a large scale
Morgado, A; Najera, F; Lagunas, A; Samitier, J; Vida, Y; Perez-Inestrosa, E POLYMER CHEMISTRY 2021
Spontaneous macrocyclization through multiple dynamic cyclic aminal formation
Carbajo D, Ruiz-Sánchez AJ, Nájera F, Pérez-Inestrosa E, Alfonso I Chemical communications (Cambridge, England) 2021 Feb 4;57(10):1190-1193
Recent patents in Allergy/Immunology: New pyrazinones for the diagnosis of allergies to aminocephalosporins
Martin-Serrano A, Perez-Inestrosa E, Mayorga C, Torres MJ, Montañez MI Allergy 2021 Apr;76(4):1288-1291
The Role of Benzylpenicilloyl Epimers in Specific IgE Recognition
Mayorga C, Montañez MI, Najera F, Bogas G, Fernandez TD, et al. Frontiers in pharmacology 2021;12():585890
Biotin-Labelled Clavulanic Acid to Identify Proteins Target for Haptenation in Serum: Implications in Allergy Studies
Martín-Serrano Á, Gonzalez-Morena JM, Barbero N, Ariza A, Sánchez Gómez FJ, et al. Frontiers in pharmacology 2020;11():594755
Coherent silicon photonic interferometric biosensor with an inexpensive laser source for sensitive label-free immunoassays
Leuermann J, Stamenkovic V, Ramirez-Priego P, Sánchez-Postigo A, Fernández-Gavela A, et al. Optics letters 2020 Dec 15;45(24):6595-6598
Cyanine-Like Boronic Acid-Derived Salicylidenehydrazone Complexes (Cy-BASHY) for Bioimaging Applications
Santos FMF, Domínguez Z, Fernandes JPL, Parente Carvalho C, Collado D, et al. Chemistry (Weinheim an der Bergstrasse, Germany) 2020 Nov 6;26(62):14064-14069
Dendritic Scaffold onto Titanium Implants. A Versatile Strategy Increasing Biocompatibility
Molina N, González A, Monopoli D, Mentado B, Becerra J, et al. Polymers 2020 Apr 1;12(4):
Design of an antigenic determinant of cefaclor: Chemical structure-IgE recognition relationship
Martín-Serrano A, Mayorga C, Barrionuevo E, Pérez N, Romano A, et al. The Journal of allergy and clinical immunology 2020 Apr;145(4):1301-1304.e4
Indolenine-Based Derivatives as Customizable Two-Photon Fluorescent Probes for pH Bioimaging in Living Cells
Benitez-Martin C, Guadix JA, Pearson JR, Najera F, Perez-Pomares JM, et al. ACS sensors 2020 Apr 24;5(4):1068-1074
MitoBlue as a tool to analyze the mitochondria-lysosome communication
Sánchez MI, Vida Y, Pérez-Inestrosa E, Mascareñas JL, Vázquez ME, et al. Scientific reports 2020 Feb 26;10(1):3528
Naphthalimide Dyes with Orthogonal Functional Groups for Click Chemistry: Attachment to Solid Supports and Applications in Drug Allergy Diagnosis
Ruiz-Sanchez AJ, Collado D, Mayorga C, Torres MJ, Perez-Inestrosa E ChemPlusChem 2020 Apr;85(4):689-693
RGD-Dendrimer-Poly(L-lactic) Acid Nanopatterned Substrates for the Early Chondrogenesis of Human Mesenchymal Stromal Cells Derived from Osteoarthritic and Healthy Donors
Rodríguez-Pereira C, Lagunas A, Casanellas I, Vida Y, Pérez-Inestrosa E, et al. Materials (Basel, Switzerland) 2020 May 13;13(10):
The Janus Role of Adhesion in Chondrogenesis
Casanellas I, Lagunas A, Vida Y, Pérez-Inestrosa E, Andrades JA, et al. International journal of molecular sciences 2020 Jul 24;21(15):
Toward Two-Photon Absorbing Dyes with Unusually Potentiated Nonlinear Fluorescence Response
Benitez-Martin C, Li S, Dominguez-Alfaro A, Najera F, Pérez-Inestrosa E, et al. Journal of the American Chemical Society 2020 Sep 2;142(35):14854-14858
A turn-on two-photon fluorescent probe for detecting lysosomal hydroxyl radicals in living cells
Benitez-Martin, C; Guadix, JA; Pearson, JR; Najera, F; Perez-Pomares, JM; Perez-Inestrosa, E SENSORS AND ACTUATORS B-CHEMICAL 2019
Detection of glycidic receptors in microalgae using glycodendrons as probes: a new tool for studies on cell surface interactions
Goncalves, CD; Figueiredo, RC; Giani, A; Collado, D; Perez-Inestrosa, E; Rojo, J; Figueredo, CC JOURNAL OF APPLIED PHYCOLOGY 2019
Extended Alkenyl and Alkynyl Benzotriazoles with Enhanced Two-Photon Absorption Properties as a Promising Alternative to Benzothiadiazoles
Torres-Moya I, Benitez-Martin C, Donoso B, Tardío C, Martín R, et al. Chemistry (Weinheim an der Bergstrasse, Germany) 2019 Dec 5;25(68):15572-15579
Identification of an antigenic determinant of clavulanic acid responsible for IgE-mediated reactions
Barbero N, Fernández-Santamaría R, Mayorga C, Martin-Serrano Á, Salas M, et al. Allergy 2019 Aug;74(8):1490-1501
pi-Extended Four-Coordinate Organoboron N,C-Chelates as Two-Photon Absorbing Chromophores
Domínguez Z, Pais VF, Collado D, Vázquez-Domínguez P, Albendín FN, et al. The Journal of organic chemistry 2019 Nov 1;84(21):13384-13393
Platinum-Doped Dendritic Structure as a Phosphorescent Label for Bacteria in Two-Photon Excitation Microscopy
Molina N, Cnudde M, Guadix JA, Perez-Pomares JM, Strassert CA, et al. ACS omega 2019 Aug 20;4(8):13027-13033
Synergistic effect between CaCl2 and gamma-Al2O3 for furfural production by dehydration of hemicellulosic carbohydrates
Funez-Nunez, I; Garcia-Sancho, C; Cecilia, JA; Moreno-Tost, R; Perez-Inestrosa, E; Serrano-Cantador, L; Maireles-Torres, P APPLIED CATALYSIS A-GENERAL 2019
Synthesis of Amino Terminal Clicked Dendrimers. Approaches to the Application as a Biomarker
Molina N, Nájera F, Guadix JA, Perez-Pomares JM, Vida Y, et al. The Journal of organic chemistry 2019 Aug 16;84(16):10197-10208
Bis(dioxaborine) Dyes with Variable pi-Bridges: Towards Two-Photon Absorbing Fluorophores with Very High Brightness
Marín ÁM, Telo JP, Collado D, Nájera F, Pérez-Inestrosa E, et al. Chemistry (Weinheim an der Bergstrasse, Germany) 2018 Feb 26;24(12):2929-2935
Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
Casanellas I, Lagunas A, Tsintzou I, Vida Y, Collado D, et al. Journal of visualized experiments : JoVE 2018 Jan 20;(131):
Dendrimeric Antigens for Drug Allergy Diagnosis: A New Approach for Basophil Activation Tests
Molina N, Martin-Serrano A, Fernandez TD, Tesfaye A, Najera F, et al. Molecules (Basel, Switzerland) 2018 Apr 24;23(5):
Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells
Sánchez-Gómez FJ, González-Morena JM, Vida Y, Pérez-Inestrosa E, Blanca M, et al. Allergy 2017 Mar;72(3):385-396
Beneficial effects of calcium chloride on glucose dehydration to 5-hydroxymethylfurfural in the presence of alumina as catalyst
Garcia-Sancho, C; Funez-Nunez, I; Moreno-Tost, R; Santamaria-Gonzalez, J; Perez-Inestrosa, E; Fierro, JLG; Maireles-Torres, P APPLIED CATALYSIS B-ENVIRONMENTAL 2017
Carborane-stilbene dyads: the influence of substituents and cluster isomers on photoluminescence properties
Ferrer-Ugalde A, Cabrera-González J, Juárez-Pérez EJ, Teixidor F, Pérez-Inestrosa E, et al. Dalton transactions (Cambridge, England : 2003) 2017 Feb 14;46(7):2091-2104
Electronic and Functional Scope of Boronic Acid Derived Salicylidenehydrazone (BASHY) Complexes as Fluorescent Dyes
Alcaide MM, Santos FMF, Pais VF, Carvalho JI, Collado D, et al. The Journal of organic chemistry 2017 Jul 21;82(14):7151-7158
Patients Taking Amoxicillin-Clavulanic Can Become Simultaneously Sensitized to Both Drugs
Salas M, Laguna JJ, Doña I, Barrionuevo E, Fernandez-Santamaría R, et al. The journal of allergy and clinical immunology. In practice 2017 May – Jun;5(3):694-702.e3
Review of analytical methodologies for the determination of 5-HT3 receptor antagonists
Bosch, ME; Sanchez, AJR; Rojas, FS; Ojeda, CB MICROCHEMICAL JOURNAL 2017
Tailoring RGD local surface density at the nanoscale toward adult stem cell chondrogenic commitment
Lagunas, A; Tsintzou, I; Vida, Y; Collado, D; Perez-Inestrosa, E; Pereira, CR; Magalhaes, J; Andrades, JA; Samitier, J NANO RESEARCH 2017
The Value of In Vitro Tests to DiminishDrug Challenges
Mayorga C, Doña I, Perez-Inestrosa E, Fernández TD, Torres MJ International journal of molecular sciences 2017 Jun 7;18(6):
Dendrimer surface orientation of the RGD peptide affects mesenchymal stem cell adhesion
Vida, Y; Collado, D; Najera, F; Claros, S; Becerra, J; Andrades, JA; Perez-Inestrosa, E RSC ADVANCES 2016
Development of nanostructures in the diagnosis of drug hypersensitivity reactions
Mayorga C, Perez-Inestrosa E, Molina N, Montañez MI Current opinion in allergy and clinical immunology 2016 Aug;16(4):300-7
Fluorescent BAPAD Dendrimeric Antigens Are Efficiently Internalized by Human Dendritic Cells
Mesa-Antunez, P; Collado, D; Vida, Y; Najera, F; Fernandez, T; Torres, MJ; Perez-Inestrosa, E POLYMERS 2016
New Advances in the Study of IgE Drug Recognition
Martin-Serrano A, Barbero N, Agundez JA, Vida Y, Perez-Inestrosa E, et al. Current pharmaceutical design 2016;22(45):6759-6772
Red-Emitting Tetracoordinate Organoboron Chelates: Synthesis, Photophysical Properties, and Fluorescence Microscopy
Pais VF, Ramírez-López P, Romero-Arenas A, Collado D, Nájera F, et al. The Journal of organic chemistry 2016 Oct 21;81(20):9605-9611
The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams
Ariza A, Mayorga C, Salas M, Doña I, Martín-Serrano Á, et al. Scientific reports 2016 Oct 12;6():35113
The role of IgE recognition in allergic reactions to amoxicillin and clavulanic acid
Torres MJ, Montañez MI, Ariza A, Salas M, Fernandez TD, et al. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2016 Feb;46(2):264-74
Effect of chemical heterogeneity on photoluminescence of graphite oxide treated with S-/N-containing modifiers
Ebrahim, AM; Rodriguez-Castellon, E; Montenegro, JM; Bandosz, TJ APPLIED SURFACE SCIENCE 2015
Highly sensitive dendrimer-based nanoplasmonic biosensor for drug allergy diagnosis
Soler M, Mesa-Antunez P, Estevez MC, Ruiz-Sanchez AJ, Otte MA, et al. Biosensors & bioelectronics 2015 Apr 15;66():115-23
Recognition of multiepitope dendrimeric antigens by human immunoglobulin E
Montañez MI, Najera F, Mayorga C, Ruiz-Sanchez AJ, Vida Y, et al. Nanomedicine : nanotechnology, biology, and medicine 2015 Apr;11(3):579-88
Strongly Emissive and Photostable Four-Coordinate Organoboron N,C Chelates and Their Use in Fluorescence Microscopy
Pais VF, Alcaide MM, López-Rodríguez R, Collado D, Nájera F, et al. Chemistry (Weinheim an der Bergstrasse, Germany) 2015 Oct 19;21(43):15369-76
Synthesis of all-aliphatic polyamide dendrimers based on a 3,3 ‘-diaminopivalic acid scaffold
Ruiz-Sanchez, AJ; Mesa-Antunez, P; Barbero, N; Collado, D; Vida, Y; Najera, F; Perez-Inestrosa, E POLYMER CHEMISTRY 2015
Enlaces
Calle Severo Ochoa, 35
Parque Tecnol?gico de Andaluc?a (PTA) Campanillas,
M?laga 29590
(+34) 951 440 260
Fax: (+34) 951 440 263